Trimethylacetic anhydride

• CAS: 1538-75-6
• Catalog Number: ACM1538756
• Category: Acylation Reagents
• Molecular Weight: 186.25
• Molecular Formula: C10H18O3
• Synonyms: 2,2-Dimethylpropionic anhydride, Pivalic anhydride
• Boiling Point: 193 °C (lit.)
• Density: 0.918 g/mL at 25 °C (lit.)
• Physical State: Liquid

Synthetic Use

Upstream Synthesis Route 1

• 124-63-0
• 75-98-9

• 3282-30-2
• 1538-75-6

Reference: [1] Tetrahedron, 1993, vol. 49, # 8, p. 1535 - 1540

Upstream Synthesis Route 2

• 75-98-9

• 3282-30-2
• 1538-75-6

Reference: [1] Tetrahedron, 1993, vol. 49, # 8, p. 1535 - 1540

Downstream Synthesis Route 1

• 75-85-4
• 1538-75-6

• 38222-83-2
• 108154-12-7
• 108154-13-8

Reference: [1] Bulletin de la Societe Chimique de France, 1986, # 2, p. 307 - 313
[2] Bulletin de la Societe Chimique de France, 1986, # 2, p. 307 - 313

Downstream Synthesis Route 2

• 58-14-0
• 1538-75-6

• 143947-40-4

Reference: [1]Goswami, Shyamaprosad; Adak, Avijit Kumar
[Tetrahedron Letters, 2002, vol. 43, # 46, p. 8371 - 8373]
[2]Taylor, Edward C.; Otiv, S. R.; Durucasu, Inci
[Heterocycles, 1993, vol. 36, # 8, p. 1883 - 1895]
[3]Nasir, M. Sarwar; Karlin, Kenneth D.; Chen, Qin; Zubieta, Jon
[Journal of the American Chemical Society, 1992, vol. 114, # 6, p. 2264 - 2265]

Downstream Synthesis Route 3

• 75-85-4
• 1538-75-6

• 38222-83-2
• 108154-12-7
• 108154-13-8

Reference: [1]Journal of the Chemical Society. Perkin transactions I,1992,p. 1811 - 1820

Downstream Synthesis Route 4

• 4599-47-7
• 1538-75-6

• 110762-12-4

Reference: [1]Bulletin de la Societe Chimique de France,1986,p. 307 - 313
[2]Bulletin de la Societe Chimique de France,1986,p. 307 - 313

* For details of the synthesis route, please refer to the original source to ensure accuracy.