Trilobatin

• CAS: 4192-90-9
• Catalog Number: ACM4192909
• Category: Inhibitors
• Molecular Weight: 436.41
• Molecular Formula: C21H24O10
• Description: Trilobatin, a natural sweetener derived from Lithocarpus polystachyus Rehd, Trilobatin is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope. Neuroprotective effects. Trilobatin is also a SGLT1/2 inhibitor that selectively induces the proliferation of human hepatoblastoma cells.

Synthetic Use

Upstream Synthesis Route 1

• 133-89-1
• 60-82-2

• 4192-90-9
• 60-81-1

Reference: [1] Organic Letters, 2014, vol. 16, # 18, p. 4874 - 4877

Upstream Synthesis Route 2

• 18916-17-1

• 4192-90-9

Reference: [1]Jorio
[Annali di Chimica, 1959, vol. 49, p. 1929,1936]

Downstream Synthesis Route 1

• 4192-90-9

• 60-82-2

Reference: [1] Annali di Chimica (Rome, Italy), 1959, vol. 49, p. 1929,1936

Downstream Synthesis Route 2

• 4192-90-9

• 60-82-2

Reference: [1]Annali di Chimica,1959,vol. 49,p. 1929,1936

* For details of the synthesis route, please refer to the original source to ensure accuracy.