Tipranavir

• CAS: 174484-41-4
• Catalog Number: ACM174484414
• Category: Inhibitors
• Molecular Weight: 602.66
• Molecular Formula: C₃₁H₃₃F₃N₂O₅S
• Description: Tipranavir (PNU-140690) inhibits the enzymatic activity and dimerization of HIV-1 protease, exerts potent activity against multi-protease inhibitor (PI)-resistant HIV-1 isolates with IC50s of 66-410 nM. Tipranavir inhibits SARS-CoV-2 3CLpro activity.
• Synonyms: PNU-140690;Aptivus;N-[3-[(1R)-1-[(6R)-5,6-Dihydro-4-hydroxy-2-oxo-6-(2-phenylethyl)-6-propyl-2H-pyran-3-yl]propyl]phenyl]-5-(trifluoromethyl)-2-pyridinesulfonamide;N-[3-[(1R)-1-[(6R)-2-Hydroxy-4-oxo-6-phenethyl-6-propyl-5H-pyran-3-yl]propyl]phenyl]-5-(trifluoromethyl)pyridine-2-sulfonamide;Tipranavir;Tipranavir(PNU-140690,Aptivus);2-PyridinesulfonaMide,N-[3-[(1R)-1-[(6R)-5,6-dihydro-4-hydroxy-2-oxo-6-(2-phenylethyl)-6-propyl-2H-pyran-3-yl]propyl]phenyl]-5-(trifluoroMethyl)-
• Canonical SMILES: O=C1C([C@H](CC)C2=CC=CC(NS(C3=CC=C(C(F)(F)F)C=N3)(=O)=O)=C2)=C(O)C[C@](CCC4=CC=CC=C4)(CCC)O1
• Melting Point: 86-890C
• Appearance: Solid
• Storage: Powder-20°C, 3 years; 4°C, 2 years; In solvent-80°C, 6 months; -20°C, 1 month.
• Shipping: Can be shipped at room temperature, where not in use may vary.

Custom Q&A

What is the molecular formula of Tipranavir?

The molecular formula of Tipranavir is C31H33F3N2O5S.

What is the molecular weight of Tipranavir?

The molecular weight of Tipranavir is 602.7 g/mol.

What are the synonyms for Tipranavir?

The synonyms for Tipranavir are Aptivus, PNU-140690, TPV.

What is the IUPAC name of Tipranavir?

The IUPAC name of Tipranavir is N-[3-[(1R)-1-[(2R)-4-hydroxy-6-oxo-2-(2-phenylethyl)-2-propyl-3H-pyran-5-yl]propyl]phenyl]-5-(trifluoromethyl)pyridine-2-sulfonamide.

What is the InChI of Tipranavir?

The InChI of Tipranavir is InChI=1S/C31H33F3N2O5S/c1-3-16-30(17-15-21-9-6-5-7-10-21)19-26(37)28(29(38)41-30)25(4-2)22-11-8-12-24(18-22)36-42(39,40)27-14-13-23(20-35-27)31(32,33)34/h5-14,18,20,25,36-37H,3-4,15-17,19H2,1-2H3/t25-,30-/m1/s1.

What is the InChIKey of Tipranavir?

The InChIKey of Tipranavir is SUJUHGSWHZTSEU-FYBSXPHGSA-N.

What is the canonical SMILES of Tipranavir?

The canonical SMILES of Tipranavir is CCCC1(CC(=C(C(=O)O1)C(CC)C2=CC(=CC=C2)NS(=O)(=O)C3=NC=C(C=C3)C(F)(F)F)O)CCC4=CC=CC=C4.

What is the CAS number of Tipranavir?

The CAS number of Tipranavir is 174484-41-4.

What is the UNII of Tipranavir?

The UNII of Tipranavir is ZZT404XD09.

What is the ChEMBL ID of Tipranavir?

The ChEMBL ID of Tipranavir is CHEMBL222559.