Tacedinaline (CI-994)

• CAS: 112522-64-2
• Catalog Number: ACM112522642
• Category: Others
• Molecular Weight: 269.30
• Molecular Formula: C15H15N3O2
• Description: Tacedinaline, also known as CI-944 and PD123654, is a n orally bioavailable substituted benzamide derivative with potential antineoplastic activity. Tacedinaline inhibits histone deacetylation, which may result in histone hyperacetylation, followed by the induction of differentiation, the inhibition of cell proliferation, and apoptosis in susceptible tumor cell populations.
• Synonyms: CI994, CI-994, CI 994, PD123654, PD-123654, PD 123654, Tacedinaline, acetyldinaline
• IUPAC Name: 4-acetamido-N-(2-aminophenyl)benzamide
• Canonical SMILES: O=C(NC1=CC=CC=C1N)C2=CC=C(NC(C)=O)C=C2
• InChI: InChI=1S/C15H15N3O2/c1-10(19)17-12-8-6-11(7-9-12)15(20)18-14-5-3-2-4-13(14)16/h2-9H,16H2,1H3,(H,17,19)(H,18,20)
• InChI Key: VAZAPHZUAVEOMC-UHFFFAOYSA-N
• Solubility: Soluble in DMSO, not in water
• Appearance: Off-white solid powder
• Shelf Life: >5 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Drug Formulation: This drug may be formulated in DMSO
• Elemental Analysis: C, 66.90; H, 5.61; N, 15.60; O, 11.88
• Exact Mass: 269.11643
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).