SJ6986

CAS
2765625-93-0
Catalog Number
ACM2765625930
Category
Others
Molecular Weight
497.40
Molecular Formula
C20H14F3N3O7S

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Specification

Description
SJ6986 is a Potent, Selective, and Orally Bioavailable Small-Molecule GSPT1/2 Degrader from a Focused Library of Cereblon Modulator.
Synonyms
SJ6986; SJ-6986; SJ 6986
IUPAC Name
N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)-2-(trifluoromethoxy)benzenesulfonamide
Canonical SMILES
O=S(C1=CC=CC=C1OC(F)(F)F)(NC2=CC3=C(C(N(C(CC4)C(NC4=O)=O)C3=O)=O)C=C2)=O
InChI
InChI=1S/C20H14F3N3O7S/c21-20(22,23)33-14-3-1-2-4-15(14)34(31,32)25-10-5-6-11-12(9-10)19(30)26(18(11)29)13-7-8-16(27)24-17(13)28/h1-6,9,13,25H,7-8H2,(H,24,27,28)
InChI Key
RKAFYSIKAVFVPS-UHFFFAOYSA-N
Solubility
To be determined
Appearance
Solid powder
Shelf Life
>2 years if stored properly
Storage
Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
Drug Formulation
To be determined
Elemental Analysis
C, 48.30; H, 2.84; F, 11.46; N, 8.45; O, 22.52; S, 6.45
Exact Mass
497.0505
HS Tariff Code
2934.99.9001
Shipping
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Stock Solution Storage
0-4 °C for short term (days to weeks), or -20 °C for long term (months).
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