20(R)-Ginsenoside Rh2

CAS

112246-15-8

Catalog Number

ACM112246158

Category

Inhibitors

Molecular Weight

622.88

Molecular Formula

C36H62O8

MSDS COA Spec Sheet

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Specification

Description

20(R)-Ginsenoside Rh2, a matrix metalloproteinase (MMP) inhibitor, acts as a cell antiproliferator. It has anticancer effects via blocking cell proliferation and causing G1 phase arrest. 20(R)-Ginsenoside Rh2 induces apoptosis, and has anti-inflammatory and antioxidative activity. 20(R)-Ginsenoside Rh2 inhibits the replication and proliferation of mouse and human gammaherpesvirus 68 (MHV-68) with an IC50 of 2.77 μM for murine MHV-68.

Synonyms

b-D-Glucopyranoside, (3b,12b,20R)-12,20-dihydroxydammar-24-en-3-yl; (3beta,12beta)-12,20-dihydroxydammar-24-en-3-yl beta-d-glucopyranoside; 20-(R)-Ginsenoside Rh2; 20(R)-Ginsenoside Rh2; 20(R)-GINSENOSIDERH2; Ginsenoside-Rh2; Ginsenoside Rh2, 20(R)-; 20(R)-Ginsenoside-Rh2; (R) Ginsenoside Rh2;

IUPAC Name

(2R,3R,4S,5S,6R)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-17-[(2R)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol

Canonical SMILES

CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CCC4C3(CCC(C4(C)C)OC5C(C(C(C(O5)CO)O)O)O)C)C)O)C)O)C

InChI

InChI=1S/C36H62O8/c1-20(2)10-9-14-36(8,42)21-11-16-35(7)27(21)22(38)18-25-33(5)15-13-26(32(3,4)24(33)12-17-34(25,35)6)44-31-30(41)29(40)28(39)23(19-37)43-31/h10,21-31,37-42H,9,11-19H2,1-8H3/t21-,22+,23+,24-,25+,26-,27-,28+,29-,30+,31-,33-,34+,35+,36+/m0/s1

InChI Key

CKUVNOCSBYYHIS-SUEBGMEDSA-N

Appearance

Powder

Storage

4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light).

Exact Mass

622.44400

Shipping

Can be shipped at room temperature, where not in use may vary.

Source

PlantsAraliaceaePanax ginseng C. A. Meyer

August 12, 2023

Highly active reagent
20(R)-Ginsenoside Rh2 has high activity, anti-inflammatory and antioxidant activities.

What is the source of 20(R)-ginsenoside Rh2?

20(R)-Ginsenoside Rh2 mainly comes from natural substance ginseng.

What is the molecular formula of 20(R)-ginsenoside Rh2?

The molecular formula of 20(R)-ginsenoside Rh2 is C36H62O8.

How to store 20(R)-ginsenoside Rh2?

20(R)-Ginsenoside Rh2 needs to be stored in a dark and low temperature environment of 2-8 C.

What is the pharmacological effect of 20(R)-ginsenoside Rh2?

20(R)-Ginsenoside Rh2 can inhibit the growth of tumor cells.

What are the precautions for using 20(R)-ginsenoside Rh2?

20(R)-Ginsenoside Rh2 should be stored at low temperature, and the content will be reduced after being exposed to air for a long time.

What is the character of 20(R)-ginsenoside Rh2?

20(R)-Ginsenoside Rh2 mainly white powder.

What is the purpose of 20(R)-ginsenoside Rh2?

20(R)-Ginsenoside Rh2 can be used in content determination, identification, pharmacological experiments, activity screening and other research fields.

What is the detection method of 20(R)-ginsenoside Rh2?

20(R)-Ginsenoside Rh2 mainly uses high performance liquid chromatography to detect purity and concentration.

What is the boiling point of 20(R)-ginsenoside Rh2?

The boiling point of 20(R)-ginsenoside Rh2 is 726.4℃ at 760 mmHg.

In which organic solvents can 20(R)-ginsenoside Rh2 be dissolved?

20(R)-Ginsenoside Rh2 can be dissolved in organic solvents such as methanol, ethanol and DMSO.