Phenoxodiol

• CAS: 81267-65-4
• Catalog Number: ACM81267654
• Category: Inhibitors
• Molecular Weight: 240.25
• Molecular Formula: C₁₅H₁₂O₃
• Description: Phenoxodiol (Idronoxil), a synthetic analog of Genestein, activates the mitochondrial caspase system, inhibits XIAP (an apoptosis inhibitor), and sensitizes the cancer cells to Fas-mediated apoptosis. Phenoxodiol also inhibits DNA topoisomerase II by stabilizing the cleavable complex. Phenoxodiol induces cell cycle arrest in the G1/S phase of the cell cycle and upregulates p21WAF1 via a p53 independent manner.
• Synonyms: DEHYDROEQUOL;7,4-DIHYDROXYISOFLAV-3-ENE;PHENOXODIOL;Haginin E;Idronoxil;3-(4-Hydroxyphenyl)-2H-1-benzopyran-7-ol;PhenoxodiolHaginin EIdronoxil;2H-1-Benzopyran-7-ol, 3-(4-hydroxyphenyl)-
• Canonical SMILES: OC1=CC=C2C=C(C3=CC=C(O)C=C3)COC2=C1
• Appearance: Solid
• Storage: Powder-20°C, 3 years; 4°C, 2 years; In solvent-80°C, 6 months; -20°C, 1 month.
• Hazard Statements: Xn,N
• Safety Description: 61
• Shipping: Can be shipped at room temperature, where not in use may vary.
• Supplemental Hazard Statements: H302-H400
• Symbol: GHS07,GHS09

Custom Q&A

What is the molecular formula of Phenoxodiol?

The molecular formula of Phenoxodiol is C15H12O3.

What are some synonyms for Phenoxodiol?

Some synonyms for Phenoxodiol include Idronoxil, Dehydroequol, and Haginin E.

What is the molecular weight of Phenoxodiol?

The molecular weight of Phenoxodiol is 240.25 g/mol.

When was Phenoxodiol created and last modified?

Phenoxodiol was created on July 19, 2005, and last modified on December 30, 2023.

What is the IUPAC name of Phenoxodiol?

The IUPAC name of Phenoxodiol is 3-(4-hydroxyphenyl)-2H-chromen-7-ol.

What is the InChIKey of Phenoxodiol?

The InChIKey of Phenoxodiol is ZZUBHVMHNVYXRR-UHFFFAOYSA-N.

What is the Canonical SMILES of Phenoxodiol?

The Canonical SMILES of Phenoxodiol is C1C(=CC2=C(O1)C=C(C=C2)O)C3=CC=C(C=C3)O.

What is the CAS number of Phenoxodiol?

The CAS number of Phenoxodiol is 81267-65-4.

How many hydrogen bond donor counts does Phenoxodiol have?

Phenoxodiol has 2 hydrogen bond donor counts.

What is the topological polar surface area of Phenoxodiol?

The topological polar surface area of Phenoxodiol is 49.7 Å2.