CAS
1926-80-3 Purity
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1926-80-3 Purity
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N-(2-Mercaptopropionyl)glycine
CAS
1953-02-2
Catalog Number
ACM1953022
Category
Amino Acids
Molecular Weight
163.19
Molecular Formula
CH3CH(SH)CONHCH2COOH
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Specification
Synonyms
Tiopronin
Canonical SMILES
CC(S)C(=O)NCC(O)=O
InChI
1S/C5H9NO3S/c1-3(10)5(9)6-2-4(7)8/h3,10H,2H2,1H3,(H,6,9)(H,7,8)
InChI Key
YTGJWQPHMWSCST-UHFFFAOYSA-N
Melting Point
98-100℃
Application
N-(2-Mercaptopropionyl)glycine or Tiopronin has been used:
in the preparation of polyethylenimine (PEI)-coated gold microparticles (PEI-gold) for biolistic delivery of nucleic acids
to study the role of reactive oxygen species (ROS) at the reperfusion stage in in vivo isoflurane preconditioning-induced neuroprotection
as a ROS inhibitor to study its effect on lysophosphatidylcholine (LPC)-induced inflammasome activation
in the preparation of polyethylenimine (PEI)-coated gold microparticles (PEI-gold) for biolistic delivery of nucleic acids
to study the role of reactive oxygen species (ROS) at the reperfusion stage in in vivo isoflurane preconditioning-induced neuroprotection
as a ROS inhibitor to study its effect on lysophosphatidylcholine (LPC)-induced inflammasome activation
Assay
≥98% (TLC)
Beilstein
1859822
Biochem Physiol Actions
N-(2-Mercaptopropionyl)glycine (NMPG) is a thiol compound associated with autoimmune hypoglycemia. It is a diffusible antioxidant and reduces the severity of colonic injury. NMPG also relieves myeloperoxidase activity and stimulates hypoxia-inducible factor-1 (HIF-1) - vascular endothelial growth factor (VEGF) pathway for ulcer healing.
Color
white
EC Number
217-778-4
Form
powder
MDL Number
MFCD00004861
NACRES
NA.26
PubChem ID
24897101
Quality Level
100
Storage Temperature
2-8℃
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