N-Boc-nortropinone

• CAS: 185099-67-6
• Catalog Number: ACM185099676
• Category: Other Products
• Molecular Weight: 225.28
• Molecular Formula: C₁₂H₁₉NO₃
• Synonyms: ZINC00057561, CID688612, ZINC00057560, 185099-67-6
• IUPAC Name: tert-butyl (1R,5S)-3-oxo-8-azabicyclo[3.2.1]octane-8-carboxylate
• Canonical SMILES: CC(C)(C)OC(=O)N1C2CCC1CC(=O)C2
• InChI Key: MENILFUADYEXNU-DTORHVGOSA-N
• Boiling Point: 325.8ºC at 760 mmHg
• Melting Point: 58-59ºC
• Flash Point: 150.8ºC
• Density: 1.139 g/cm³
• Appearance: off-white solid
• Exact Mass: 225.13600
• Hazard Statements: Xi:Irritant
• H-Bond Acceptor: 3
• H-Bond Donor: 0
• Safety Description: 26-39
• WGK Germany: 3

Synthetic Use

Upstream Synthesis Route 1

• 24424-99-5
• 5632-84-8

• 185099-67-6

Reference: [1] Bioorganic and Medicinal Chemistry Letters, 2003, vol. 13, # 20, p. 3597 - 3600

Upstream Synthesis Route 2

• 24424-99-5
• 25602-68-0

• 185099-67-6

Reference: [1] Patent: US2009/318493, 2009, A1, . Location in patent: Page/Page column 41-42

Upstream Synthesis Route 3

• 28957-72-4
• 24424-99-5

• 185099-67-6

Reference: [1] Patent: US2006/100426, 2006, A1, . Location in patent: Page/Page column 18

Upstream Synthesis Route 4

• 24424-99-5
• 5632-84-8

• 185099-67-6

Reference: [1]Bioorganic and Medicinal Chemistry Letters,2003,vol. 13,p. 3597 - 3600

Downstream Synthesis Route 1

• 867-13-0
• 185099-67-6

• 865106-60-1

Reference: [1]Patent: US2005/209226,2005,A1

* For details of the synthesis route, please refer to the original source to ensure accuracy.