Monoolein

• CAS: 25496-72-4
• Catalog Number: ACM25496724-2
• Category: Main Products
• Molecular Weight: 356.54
• Molecular Formula: C21H40O4
• Synonyms: Monoolein; Monooleate Glycerol; 2,3-dihydroxypropyl (E)-octadec-9-enoate; Glycerol .alpha.-monooleate
• IUPAC Name: Glycerol mono-oleate
• Boiling Point: 483.3ºC at 760 mmHg
• Melting Point: 35-37°C
• Flash Point: 425°F
• Density: 0.96 g/cm³ (25 ºC)
• Appearance: white waxy paste
• Storage: Freezer
• Alpha Sort: Glycerol monooleate
• Exact Mass: 356.29300
• Physical State: Liquid

Case Study

Monoolein for the preparation of quercetin-loaded liquid crystalline nanoparticles (LCNs)

Yong DOC, et al. Journal of Drug Delivery Science and Technology, 2019, 54, 101297.

Monoolein (MO) plays a crucial role in the formulation of liquid crystalline nanoparticles (LCNs) for the encapsulation of quercetin, leveraging its ability to form a liquid crystalline cubic phase. In the described process, MO is melted with quercetin at 45°C, forming a mixture that is then combined with a P 407 solution, also heated to the same temperature. This mixture undergoes vortex mixing, followed by ultrasonication for 10 minutes at 60% amplitude to stabilize the liquid crystalline structure. The resulting LCNs exhibit potential for drug delivery, particularly for the controlled release of quercetin. Monoolein's role as a surfactant and matrix-forming agent enhances the stability and encapsulation efficiency of bioactive compounds, making it highly suitable for pharmaceutical and biotechnological applications in nanocarrier-based drug delivery systems.

Monoolein as a Template for the Synthesis of Gold Nanoparticles

Park SC, et al. Journal of Industrial and Engineering Chemistry, 2023, 121, 2023, 132-141.

Monoolein (MO) has been utilized as a template for the preparation of gold nanoparticles (AuNPs) through a melt and hydration method. In this process, a solution of gold(III) chloride trihydrate is introduced into molten MO, with the gold ions forming nanoparticles within the cubic phase structure. The synthesis process involves the careful addition of gold ion solution to the MO melt, followed by incubation at 25°C for one week, leading to the formation of a clear gel. The concentration of gold ions, ranging from 1 to 5 mM, influences the final cubic phase (CP), with varying concentrations of gold resulting in different nanoparticle characteristics. The resulting gold nanoparticles can be employed in a variety of applications, including catalysis, drug delivery, and sensing, where the cubic phase of MO provides a stable, organized environment for nanoparticle growth. This method demonstrates the versatility of MO as a template material for the controlled synthesis of metal nanoparticles with potential applications in nanomedicine and materials science.

Custom Q&A

What is the molecular formula of monoolein?

The molecular formula of monoolein is C21H40O4.

What are some synonyms for monoolein?

Some synonyms for monoolein include glyceryl monooleate, 1-monoolein, and oleoylglycerol.

What is the Chemical Abstracts Service (CAS) number for monoolein?

The CAS number for monoolein is 111-03-5.

What is the three-dimensional structure of monoolein?

The three-dimensional structure of monoolein is not provided in the reference.

What are some common applications or uses of monoolein?

The reference does not provide information on the applications or uses of monoolein.

What is the safety information for monoolein?

The reference does not provide specific safety information for monoolein.

What are some other chemicals or compounds that monoolein can be synthesized into?

The reference does not provide information on other chemicals or compounds synthesized from monoolein.

What is the International Union of Pure and Applied Chemistry (IUPAC) name for monoolein?

The IUPAC name for monoolein is not provided in the reference.

Are there any known hazards or risks associated with handling or using monoolein?

The reference does not provide information on specific hazards or risks associated with monoolein.

What physical properties or characteristics does monoolein have?

The reference does not provide information on the specific physical properties or characteristics of monoolein.