MNK8

• CAS: 2055078-49-2
• Catalog Number: ACM2055078492
• Category: Inhibitors
• Molecular Weight: 252.27
• Molecular Formula: C15H12N2O2
• Description: MNK8 is a novel inhibitor of STAT3 activation, reducing DNA binding ability, increasing SubG1 cell population and inducing apoptosis in HCC cells.
• Synonyms: MNK8; MNK 8; MNK-8
• IUPAC Name: 3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione
• Canonical SMILES: O=C1N(C)C(C=C(C2=C3C=CC=CC3=CC=C2)N1)=O
• InChI: InChI=1S/C15H12N2O2/c1-17-14(18)9-13(16-15(17)19)12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,16,19)
• InChI Key: SJRMGNRXVMMJSY-UHFFFAOYSA-N
• Solubility: To be determined
• Appearance: Solid powder
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Drug Formulation: To be determined
• Elemental Analysis: C, 71.42; H, 4.79; N, 11.10; O, 12.68
• Exact Mass: 252.0899
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).