Laninamivir Octanoate

• CAS: 203120-46-1
• Catalog Number: ACM203120461-1
• Category: Inhibitors
• Molecular Weight: 472.54
• Molecular Formula: C21H36N4O8
• Description: Laninamivir Octanoate, also known as CS-8958, is a long acting neuraminidase inhibitor which shows superior anti-influenza virus activity. Laninamivir octanoate and artificial surfactant combination therapy significantly increases survival of mice infected with lethal influenza H1N1 Virus. A single intranasal administration of CS-8958 showed a superior reduction of virus load in lungs in mouse infection model.
• Synonyms: Laninamivir Octanoate; CS-8958; CS 8958; CS8958; R-125489; R 125489; R125489
• IUPAC Name: (4S,5R,6R)-5-Acetamido-4-guanidino-6-[(1R,2R)- 2-hydroxy-1-methoxy-3-(octanoyloxy)propyl]-5,6-dihydro-4H-pyran-2-carboxylic Acid
• Canonical SMILES: O=C(C1=C[C@H](NC(N)=N)[C@@H](NC(C)=O)[C@H]([C@H](OC)[C@H](O)COC(CCCCCCC)=O)O1)O
• InChI: InChI=1S/C21H36N4O8/c1-4-5-6-7-8-9-16(28)32-11-14(27)18(31-3)19-17(24-12(2)26)13(25-21(22)23)10-15(33-19)20(29)30/h10,13-14,17-19,27H,4-9,11H2,1-3H3,(H,24,26)(H,29,30)(H4,22,23,25)/t13-,14+,17+,18+,19+/m0/s1
• InChI Key: UKTIJASCFRNWCB-RMIBSVFLSA-N
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Shelf Life: >3 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Alternative CAS: 203120-17-6 (free base); 203120-18-7 (TFA); 203120-46-1 (octanoate); 1233643-88-3 (octanoate hydrate)
• Drug Formulation: This drug may be formulated in DMSO
• Elemental Analysis: C, 53.38; H, 7.68; N, 11.86; O, 27.09
• Exact Mass: 472.2533
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).