Specification
Description
L-Glutamine is a multifunctional amino acid that plays an important role in various metabolic processes in the human body. This non-essential amino acid is naturally abundant and contributes significantly to a variety of important functions.
Synonyms
(S)-2,5-Diamino-5-oxopentanoic acid, L-Glutamic acid 5-amide, Levoglutamide
IUPAC Name
(2S)-2,5-Diamino-5-oxopentanoic acid
Canonical SMILES
N[C@@H](CCC(N)=O)C(O)=O
InChI
1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1
InChI Key
ZDXPYRJPNDTMRX-VKHMYHEASA-N
Melting Point
185 ℃(dec.) (lit.)
Density
1.47 g/cm³ at 20 °C
Solubility
1 M HCl: 50 mg/mL, clear to slightly hazy, colorless
Application
L-Glutamine has been used to study the effects of amino acids in promoting food consumption in Drosophila melanogaster.It has also been used to study non-enzymatic gluconeogenesis.
Storage
Store below +30 °C
Biochem Physiol Actions
L-glutamine is the most abundant amino acid in the body. It is essential for the synthesis of L-asparagine. L-glutamic acid aids the incorporation of NH4+ into biomolecules.
Feature
One of its main functions is to serve as a carrier of the main amino acid nitrogen in the body. It is a transporter of nitrogen, an essential component of many biological processes. Additionally, L-glutamine is the primary energy source for many types of cells, ensuring they have the energy they need to function optimally.
L-Glutamine is essential for maintaining the delicate balance of ammonia in the body. This balance is critical to preventing toxic ammonia levels. Another important function of L-glutamine is its contribution to providing nitrogen for a variety of anabolic processes. These processes are essential for building key molecules, including purines, which are essential for DNA production. This amino acid also provides carbon to supplement the citric acid cycle, a process central to energy production within cells.
Gene Information
rat Ggt1(116568)
Impurity Content
≤0.2% free ammonia.
~0.5% Glutamic acid
Isomeric SMILES
C(CC(=O)N)[C@@H](C(=O)O)N
Monoisotopic Mass
146.06914219
pH
5.0-6.0 (0.1M, H₂O, 25°C)
Refractive Index
6.8 ° (C=4, H₂O)
Stability
Stability Moisture and light sensitive. Incompatible with moisture, strong oxidizing agents.
Topological Polar Surface Area
106 Ų