KG-5

• CAS: 877874-85-6
• Catalog Number: ACM877874856
• Category: Inhibitors
• Molecular Weight: 459.45
• Molecular Formula: C20H16F3N7OS
• Description: KG-5 is an orally available PDGFRß and B-Raf allosteric inhibitor.
• Synonyms: KG-5; KG 5; KG5
• IUPAC Name: 2-(Methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]-4-pyrimidinamine
• Canonical SMILES: NC1=NC(SC)=NC(OC2=CC=C(C3=NNC(NC4=CC=CC(C(F)(F)F)=C4)=N3)C=C2)=C1
• InChI: InChI=1S/C20H16F3N7OS/c1-32-19-26-15(24)10-16(27-19)31-14-7-5-11(6-8-14)17-28-18(30-29-17)25-13-4-2-3-12(9-13)20(21,22)23/h2-10H,1H3,(H2,24,26,27)(H2,25,28,29,30)
• InChI Key: CMYHZFCJPORPHY-UHFFFAOYSA-N
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Shelf Life: >3 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Drug Formulation: This drug may be formulated in DMSO
• Elemental Analysis: C, 52.28; H, 3.51; F, 12.41; N, 21.34; O, 3.48; S, 6.98
• Exact Mass: 459.1089
• HS Tariff Code: 2934.99.03.00
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).