Structure

Ilaprazole

CAS
172152-36-2
Catalog Number
ACM172152362
Category
Inhibitors
Molecular Weight
366.44
Molecular Formula
C19H18N4O2S

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Specification

Description
Ilaprazole (IY-81149) is an orally active proton pump inhibitor. Ilaprazole irreversibly inhibits H+/K+-ATPase in a dose-dependent manner with an IC50 of pump inhibitory activity of 6 μM in rabbit parietal cell preparation. Ilaprazole is used for the research of gastric ulcers. Ilaprazole is also a potent TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor.
Synonyms
Ilaprazole;2-[[(4-Methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-6-(1H-pyrrol-1-yl)-1H-benzimidazole
Canonical SMILES
O=S(C1=NC2=CC=C(N3C=CC=C3)C=C2N1)CC4=NC=CC(OC)=C4C
Appearance
Solid
Storage
Powder-20°C, 3 years; 4°C, 2 years; *The compound is unstable in solutions, freshly prepared is recommended..
Shipping
Can be shipped at room temperature, where not in use may vary.
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