Gimatecan

• CAS: 292618-32-7
• Catalog Number: ACM292618327
• Category: Inhibitors
• Molecular Weight: 447.4831 g/mol
• Molecular Formula: C25H25N3O5
• Description: Gimatecan (ST1481) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity.
• Synonyms: LBQ707; LBQ 707; LB-Q707; ST1481; ST1481; ST-1481; CPT 1847; CPT-1847; CPT1847; Gimatecan
• IUPAC Name: (4S)-11-((E)-((1,1-Dimethylethoxy)imino)methyl)-4-ethyl-4-hydroxy-1,12-dihydro-14H-pyrano(3,4:6,7)indolizino(1,2-b)quinoline-3,14(4H)-dione
• Canonical SMILES: O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C(/C=N/OC(C)(C)C)C5=CC=CC=C5N=C4C3=C2)=O
• InChI: InChI=1S/C25H25N3O5/c1-5-25(31)18-10-20-21-16(12-28(20)22(29)17(18)13-32-23(25)30)15(11-26-33-24(2,3)4)14-8-6-7-9-19(14)27-21/h6-11,31H,5,12-13H2,1-4H3/b26-11+/t25-/m0/s1
• InChI Key: UIVFUQKYVFCEKJ-OPTOVBNMSA-N
• Appearance: Solid powder
• Shelf Life: >5 years if stored properly
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• Drug Formulation: This drug may be formulated in DMSO
• Elemental Analysis: C, 67.10; H, 5.63; N, 9.39; O, 17.88
• Exact Mass: 447.17942
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).