CAS
19103-54-9 Purity
98%
19103-54-9 Purity
98%
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Gardenin A
CAS
21187-73-5
Catalog Number
ACM21187735-1
Category
Inhibitors
Molecular Weight
418.4
Molecular Formula
C21H22O9
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- Product Description
- Case Study
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- Synthetic Use
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Specification
Description
Gardenin A is an orally active and synthetic PMF analogue with the neurotrophic effect for neurite outgrowth and neuronal differentiation. Gardenin A promotes neuritogenesis via activating MAPK/ERK, PKC, and PKA, but not TrkA, CREB signaling pathways. Gardenin A also has sedative, anxiolytic, antidepressant, and anticonvulsant effects.
IUPAC Name
5-hydroxy-6,7,8-trimethoxy-2-(3,4,5-trimethoxyphenyl)chromen-4-one
Canonical SMILES
COC1=CC(=CC(=C1OC)OC)C2=CC(=O)C3=C(C(=C(C(=C3O2)OC)OC)OC)O
InChI
InChI=1S/C21H22O9/c1-24-13-7-10(8-14(25-2)17(13)26-3)12-9-11(22)15-16(23)19(27-4)21(29-6)20(28-5)18(15)30-12/h7-9,23H,1-6H3
InChI Key
MQBFFYQCZCKSBX-UHFFFAOYSA-N
Appearance
Powder
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping
Can be shipped at room temperature, where not in use may vary.
Source
PlantsRutaceaeCitrus reticulata Blanco
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