Structure

Fmoc-Phe(CF2PO3)-OH

CAS
160751-44-0
Catalog Number
ACM160751440-1
Category
Amino Acids
Molecular Weight
517.42

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Specification

Description
Building block for the introduction by Fmoc SPPS. of the hydrolytically stable phosphotyrosine analog phosphonodifluoromethylphenylalanine (F2Pmp). The pKa of F2Pmp more closely resembles that of a phosphate group making it better analog than phosphonomethylphenylalanine.
Synonyms
Fmoc-Phe(CF2PO3)-OH, Fmoc-F 2Pmp-OH,Fmoc-L-p-(phosphono-difluoromethyl)phenylalanine
InChI
1S/C25H22F2NO7P/c26-25(27,36(32,33)34)16-11-9-15(10-12-16)13-22(23(29)30)28-24(31)35-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,28,31)(H,29,30)(H2,32,33,34)/t22-/m0/s1
InChI Key
XKWYQNFAGUNPJV-QFIPXVFZSA-N
Application
Peptide synthesis.
Assay
≥90.0% (HPLC)
Form
powder
Functional Group
Fmoc
MDL Number
MFCD01317828
Quality Level
200
Reaction Suitability
reaction type: Fmoc solid-phase peptide synthesis
Storage Temperature
2-8℃
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