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Structure

Fmoc-Nalpha-methyl-L-norvaline

CAS
252049-05-1
Catalog Number
ACM252049051-1
Category
Amino Acids
Molecular Weight
353.4
Molecular Formula
C21H23NO4

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Specification

Description
FMOC-Lys(Mtt)-OH is a derivative of lysine and is widely used in the field of chemistry and biochemistry. It is a white crystalline powder with a molecular weight of 545.66 g/mol. The compound is composed of two parts; the FMOC group and the Lys(Mtt) group. The FMOC group is a protecting group while the Lys(Mtt) group is a side chain of the amino acid lysine. The compound is commonly used as a building block in solid-phase peptide synthesis and a reagent for protein labeling for mass spectrometry.
Synonyms
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)pentanoic acid, FMOC-Lys(Mtt)-OH
IUPAC Name
(2S)-2-[9H-fluoren-9-ylmethoxycarbonyl(methyl)amino]pentanoic acid
Canonical SMILES
CCCC(C(=O)O)N(C)C(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
InChI
1S/C21H23NO4/c1-3-8-19(20(23)24)22(2)21(25)26-13-18-16-11-6-4-9-14(16)15-10-5-7-12-17(15)18/h4-7,9-12,18-19H,3,8,13H2,1-2H3,(H,23,24)/t19-/m0/s1
InChI Key
HKELUUGCKFRJQM-IBGZPJMESA-N
Boiling Point
533.1±29.0 ℃at 760 mmHg
Melting Point
130.0 to 135.0 ℃
Flash Point
276.2±24.3 ℃
Density
1.2±0.1 g/cm3
Application
FMOC-Lys(Mtt)-OH has diverse applications in different scientific experiments. The compound is commonly used as a building block in solid-phase peptide synthesis, a reagent for protein labeling for mass spectrometry, and a protective group for amino acids. The compound has also been used in the synthesis of natural products and bioactive peptides.
Exact Mass
353.16272
Form
solid
Functional Group
Fmoc
HS Code
2935 90 90
LogP
5.09
PSA
66.84
Refractive Index
1.589
Storage Temperature
4 ℃
Type
Unusual Amino Acids, N-α-Methyl Amino Acids
Vapor Pressure
0.0±1.5 mmHg at 25℃
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