Specification
Description
FMOC-Lys(Mtt)-OH is a derivative of lysine and is widely used in the field of chemistry and biochemistry. It is a white crystalline powder with a molecular weight of 545.66 g/mol. The compound is composed of two parts; the FMOC group and the Lys(Mtt) group. The FMOC group is a protecting group while the Lys(Mtt) group is a side chain of the amino acid lysine. The compound is commonly used as a building block in solid-phase peptide synthesis and a reagent for protein labeling for mass spectrometry.
Synonyms
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)pentanoic acid, FMOC-Lys(Mtt)-OH
IUPAC Name
(2S)-2-[9H-fluoren-9-ylmethoxycarbonyl(methyl)amino]pentanoic acid
Canonical SMILES
CCCC(C(=O)O)N(C)C(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
InChI
1S/C21H23NO4/c1-3-8-19(20(23)24)22(2)21(25)26-13-18-16-11-6-4-9-14(16)15-10-5-7-12-17(15)18/h4-7,9-12,18-19H,3,8,13H2,1-2H3,(H,23,24)/t19-/m0/s1
InChI Key
HKELUUGCKFRJQM-IBGZPJMESA-N
Boiling Point
533.1±29.0 ℃at 760 mmHg
Melting Point
130.0 to 135.0 ℃
Application
FMOC-Lys(Mtt)-OH has diverse applications in different scientific experiments. The compound is commonly used as a building block in solid-phase peptide synthesis, a reagent for protein labeling for mass spectrometry, and a protective group for amino acids. The compound has also been used in the synthesis of natural products and bioactive peptides.
Type
Unusual Amino Acids, N-α-Methyl Amino Acids
Vapor Pressure
0.0±1.5 mmHg at 25℃