Structure

Fmoc-Leu-(Dmb)Gly-OH

Catalog Number
ACMA00051111
Category
Amino Acids
Molecular Weight
560.64

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Specification

Description
Fmoc-Aaa-(Dmb)Gly-OH dipeptides offer the same benefits as pseudoproline dipeptides in Fmoc SPPS but for peptide sequences containing Gly. They are extremely easy to use. Standard coupling methods like PyBOP/DIPEA or DIPCDI/HOBt can be used for their introduction. Removal of the Dmb group and regeneration of the glycine residue occurs during the course of standard TFA-mediated cleavage reaction.
Synonyms
Fmoc-Leu-(Dmb)Gly-OH, N-α-Fmoc-L-leucyl-N-α-(2,4-dimethoxybenzyl)-glycine
Application
Peptide synthesis.
Assay
≥90.0% (acidimetric)
≥97.0% (HPLC)
≥98% (TLC)
Form
powder
Functional Group
Fmoc
Quality Level
200
Reaction Suitability
reaction type: Fmoc solid-phase peptide synthesis
Storage Temperature
2-8℃
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