Structure

Fmoc-L-(2,6-di-Me)Tyr-OH

CAS
206060-54-0
Catalog Number
ACM206060540
Category
Amino Acids
Molecular Weight
431.5
Molecular Formula
C26H25NO5

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Specification

Description
Fmoc-2,6-dimethyl-L-tyrosine is a derivative of L-tyrosine, which is one of the 20 naturally occurring amino acids. It is an acronym for 9-Fluorenylmethyloxycarbonyl-2,6-dimethyltyrosine. Fmoc-2,6-dimethyl-L-tyrosine is also referred to as fluorenylmethoxycarbonyl-2,6-dimethyltyrosine or Fmoc-Dmt-OH. Fmoc-Dmt-OH has a molecular weight of 393.45 and a molecular formula of C23H21NO5.
Synonyms
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2,6-dimethyl-L-tyrosine, Fmoc-2,6-dimethyl-L-tyrosine, (S)-N-Fmoc-2,6-Dimethyltyrosine
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-hydroxy-2,6-dimethylphenyl)propanoic acid
Canonical SMILES
CC1=CC(=CC(=C1CC(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)C)O
InChI
1S/C26H25NO5/c1-15-11-17(28)12-16(2)22(15)13-24(25(29)30)27-26(31)32-14-23-20-9-5-3-7-18(20)19-8-4-6-10-21(19)23/h3-12,23-24,28H,13-14H2,1-2H3,(H,27,31)(H,29,30)/t24-/m0/s1
InChI Key
RHSSAHKTHNKPGU-DEOSSOPVSA-N
Boiling Point
691.2±55.0 ℃at 760 mmHg
Flash Point
371.8±31.5 ℃
Density
1.290 g/cm3
Application
Fmoc-2,6-dimethyl-L-tyrosine has several research applications, including the synthesis of peptides, proteins, and peptidomimetics. It is also used as a building block of combinatorial libraries for the discovery of new drug candidates. Fmoc-2,6-dimethyl-L-tyrosine has been incorporated into various bioactive peptides and proteins to improve their stability, activity, and specificity. It has also been used as a precursor for the synthesis of novel peptidomimetics with potential therapeutic applications.
Exact Mass
431.173279
Functional Group
Fmoc
HS Code
2924299090
LogP
5.59
MDL Number
MFCD01860305
PSA
99.35
Refractive Index
1.636
Storage Temperature
4 ℃
Type
Unusual Amino Acids, Analogs of Phenylalanine and Tyrosine
Vapor Pressure
0.0±2.3 mmHg at 25℃
WGK Germany
3
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