CAS
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Fmoc-His(MBom)-OH
Catalog Number
ACMA00051104
Category
Amino Acids
Molecular Weight
527.57
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Specification
Description
A novel histidine derivative for Fmoc SPPS in which the π-imidazole nitrogen is blocked with the acid-labile MBom group, In contrast to Fmoc-His(Trt)-OH, coupling of this derivative is free from the risk of racemization, even under base-mediated coupling conditions. Methoxyamine should be added to the cleavage mixture to scavenge liberated formaldehyde.
Synonyms
Fmoc-His(MBom)-OH, N-α-Fmoc-N-π-(p-methoxybenzyloxymethyl)-L-histidine
Application
Peptide synthesis.
Form
powder
Functional Group
Fmoc
Quality Level
200
Reaction Suitability
reaction type: Fmoc solid-phase peptide synthesis
Storage Temperature
15-25℃
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