Specification
Description
Fmoc-5-fluoro-DL-tryptophan is a derivative of the amino acid tryptophan. It is commonly used as a building block in peptide synthesis due to its enhanced hydrophobicity and stability compared to other tryptophan analogs. The Fmoc group is a protecting group used to protect the reactive functional groups during peptide synthesis.
Synonyms
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-5-fluorotryptophan
IUPAC Name
2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(5-fluoro-1H-indol-3-yl)propanoic acid
Canonical SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC4=CNC5=C4C=C(C=C5)F)C(=O)O
InChI
1S/C26H21FN2O4/c27-16-9-10-23-21(12-16)15(13-28-23)11-24(25(30)31)29-26(32)33-14-22-19-7-3-1-5-17(19)18-6-2-4-8-20(18)22/h1-10,12-13,22,24,28H,11,14H2,(H,29,32)(H,30,31)
InChI Key
GIFXTRKMFUWKHR-UHFFFAOYSA-N
Boiling Point
713.9±60.0 ℃at 760 mmHg
Application
Fmoc-5-fluoro-DL-tryptophan has a wide range of applications in scientific research. It is commonly used as a building block in peptide synthesis and has been used to study enzyme function and to develop novel therapeutic agents such as anticancer drugs.
Type
Unusual Amino Acids, Analogs of Tryptophan
Vapor Pressure
0.0±2.4 mmHg at 25℃