Fmoc-5-fluoro-DL-tryptophan

CAS
138775-55-0
Catalog Number
ACM138775550
Category
Amino Acids
Molecular Weight
444.5
Molecular Formula
C26H21FN2O4

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Specification

Description
Fmoc-5-fluoro-DL-tryptophan is a derivative of the amino acid tryptophan. It is commonly used as a building block in peptide synthesis due to its enhanced hydrophobicity and stability compared to other tryptophan analogs. The Fmoc group is a protecting group used to protect the reactive functional groups during peptide synthesis.
Synonyms
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-5-fluorotryptophan
IUPAC Name
2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(5-fluoro-1H-indol-3-yl)propanoic acid
Canonical SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC4=CNC5=C4C=C(C=C5)F)C(=O)O
InChI
1S/C26H21FN2O4/c27-16-9-10-23-21(12-16)15(13-28-23)11-24(25(30)31)29-26(32)33-14-22-19-7-3-1-5-17(19)18-6-2-4-8-20(18)22/h1-10,12-13,22,24,28H,11,14H2,(H,29,32)(H,30,31)
InChI Key
GIFXTRKMFUWKHR-UHFFFAOYSA-N
Boiling Point
713.9±60.0 ℃at 760 mmHg
Flash Point
385.6±32.9 ℃
Density
1.4±0.1 g/cm3
Application
Fmoc-5-fluoro-DL-tryptophan has a wide range of applications in scientific research. It is commonly used as a building block in peptide synthesis and has been used to study enzyme function and to develop novel therapeutic agents such as anticancer drugs.
Exact Mass
444.148529
Functional Group
Fmoc
LogP
5.47
MDL Number
MFCD02682359
Refractive Index
1.678
Storage Temperature
4 ℃
Type
Unusual Amino Acids, Analogs of Tryptophan
Vapor Pressure
0.0±2.4 mmHg at 25℃
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