Fmoc-D-Dpr(ivDde)-OH

• CAS: 1228900-15-9
• Catalog Number: ACM1228900159-1
• Category: Amino Acids
• Molecular Weight: 532.63
• Description: This orthogonally-protected derivative is based on the hindered Dde variant ivDde. It has very similar chemical properties to Fmoc-Lys(Dde)-OH, except that the side-chain ivDde group is considerably more stable to piperidine than Dde, and is less prone to migrate from protected to unprotected lysine side-chains. When removing ivDde in the presence of allyl based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group. Guide to Selection of Orthogonally-Protected Building Blocks for Fmoc SPPS
• Synonyms: Fmoc-D-Dpr(ivDde)-OH, N-α-Fmoc-N-β-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-D-diaminopropionic acid
• Application: Peptide synthesis.
• Assay: ≥90.0% (acidimetric); ≥95.0% (HPLC); ≥98% (TLC)
• Form: powder
• Functional Group: amine
• Quality Level: 200
• Reaction Suitability: reaction type: Fmoc solid-phase peptide synthesis
• Storage Temperature: 15-25℃