Fmoc-Cys(Dpm)-OH

CAS

247595-29-5

Catalog Number

ACM247595295

Category

Amino Acids

Molecular Weight

509.62

MSDS COA Spec Sheet

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Specification

Description

The Dpm group has increased stability compared to Trt, enabling selective removal of Mtt groups on the solid phase with dilute TFA without loss of Dpm groups. Furthermore, the Dpm group is removed by treatment with 95% TFA cleavage cocktails. Racemization during carboxyl activation is lower with this derivative than with Fmoc-Cys(Trt)-OH.

Synonyms

Fmoc-Cys(Dpm)-OH, N-α-Fmoc-S-diphenylmethyl-L-cysteine

InChI

1S/C31H27NO4S/c33-30(34)28(20-37-29(21-11-3-1-4-12-21)22-13-5-2-6-14-22)32-31(35)36-19-27-25-17-9-7-15-23(25)24-16-8-10-18-26(24)27/h1-18,27-29H,19-20H2,(H,32,35)(H,33,34)/t28-/m0/s1

InChI Key

IVPLDYIPIHKRET-NDEPHWFRSA-N

Application

Peptide synthesis.

Form

powder

Functional Group

thiol

Quality Level

200

Reaction Suitability

reaction type: Fmoc solid-phase peptide synthesis