Fmoc-azidolysine

• CAS: 159610-89-6
• Catalog Number: ACM159610896
• Category: Amino Acids
• Molecular Weight: 394.42
• Molecular Formula: C21H22N4O4
• Description: A useful tool for the synthesis of branched, side-chain modified and cyclic peptides and peptide tools for click chemistry by Fmoc SPPS. The side-chain azido group is completely stable to piperidine and TFA, but can be readily converted to an amine on the solid phase or in solution by reduction with thiols or phosphines.
• Synonyms: Fmoc-azidolysine
• InChI: 1S/C21H22N4O4/c22-25-23-12-6-5-11-19(20(26)27)24-21(28)29-13-18-16-9-3-1-7-14(16)15-8-2-4-10-17(15)18/h1-4,7-10,18-19H,5-6,11-13H2,(H,24,28)(H,26,27)/t19-/m0/s1
• InChI Key: PJRFTUILPGJJIO-IBGZPJMESA-N
• Melting Point: 78 ℃
• Application: Peptide synthesis.
• Assay: ≥98.0% (HPLC)
• Exact Mass: 394.164093
• Form: powder
• Functional Group: azide
• LogP: 4.04
• PSA: 128.87
• Quality Level: 200
• Reaction Suitability: reaction type: Fmoc solid-phase peptide synthesis
• Storage Temperature: 15-25℃
• Type: Unusual Amino Acids, Azide and Alkyne containing Amino Acids

Synthetic Use

Upstream Synthesis Route 1

• 105047-45-8

• 159610-89-6

Reference: [1] European Journal of Organic Chemistry, 2015, vol. 2015, # 5, p. 1117 - 1129

Upstream Synthesis Route 2

• 71989-26-9

• 159610-89-6

Reference: [1] Chemical Communications (Cambridge, United Kingdom), 2012, vol. 48, # 80, p. 10007 - 10009,3

Upstream Synthesis Route 3

• 82911-69-1
• 159610-92-1

• 159610-89-6

Reference: [1] European Journal of Organic Chemistry, 2008, # 31, p. 5308 - 5314

Upstream Synthesis Route 4

• 105047-45-8

• 159610-89-6

Reference: [1]European Journal of Organic Chemistry,2015,vol. 2015,p. 1117 - 1129