Fmoc-3-azabicyclo[3.1.0]hexane-2-carboxylic Acid

• CAS: 1219181-14-2
• Catalog Number: ACM1219181142
• Category: Amino Acids
• Molecular Weight: 349.4
• Molecular Formula: C21H19NO4
• Description: Fmoc-trans-3-azabicyclo[3.1.0]hexane-2-carboxylicacid is a chemical compound that has gained significant attention in the scientific community due to its potential therapeutic and industrial applications. This paper aims to provide an overview of the synthesis, chemical structure, biological activity, and potential applications of Fmoc-trans-3-azabicyclo[3.1.0]hexane-2-carboxylicacid.
• Synonyms: Fmoc-trans-3-azabicyclo[3.1.0]hexane-2-carboxylic acid
• IUPAC Name: 3-(9H-fluoren-9-ylmethoxycarbonyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid
• Canonical SMILES: C1C2C1C(N(C2)C(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35)C(=O)O
• InChI: 1S/C21H19NO4/c23-20(24)19-17-9-12(17)10-22(19)21(25)26-11-18-15-7-3-1-5-13(15)14-6-2-4-8-16(14)18/h1-8,12,17-19H,9-11H2,(H,23,24)
• InChI Key: BTOGCFAOJIQONJ-UHFFFAOYSA-N
• Application: In medical research, Fmoc-trans-3-azabicyclo[3.1.0]hexane-2-carboxylicacid has been investigated for its role in drug development. It has been used as a starting material for the synthesis of peptide-based drugs, particularly those targeting DPP-4. Clinical trials have been conducted to investigate the efficacy and safety of these drugs in the treatment of diabetes. Benefits of these drugs include improved glucose control and reduced risk of hypoglycemia. However, potential side effects include gastrointestinal disturbances and increased risk of infections.
• Exact Mass: 349.131
• Functional Group: Fmoc
• HS Code: 2933990090
• LogP: 3.2783
• PSA: 66.84
• Storage Temperature: 4 ℃
• Type: Unusual Amino Acids, Heterocyclic Amino Acids