Structure

Filipin Iii

CAS
480-49-9
Catalog Number
ACM480499
Category
Inhibitors
Molecular Weight
654.83
Molecular Formula
C35H58O11

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Specification

Description
Filipin III is the major component of Filipin, a 28-membered ring pentaene macrolide antifungal antibiotic produced by S. filipinensis, S. avermitilis and S. miharaensis. Filipin interacts with membrane sterols causing the alteration of membrane structure.
Synonyms
16,20,22,24-Octacosapentenoic Acid
IUPAC Name
(3R,4S,6S,8S,10R,12R,14R,16S,17E,19E,21E,23E,25E,27S,28R)-4,6,8,10,12,14,16,27-octahydroxy-3-[(1R)-1-hydroxyhexyl]-17,28-dimethyl-1-oxacyclooctacosa-17,19,21,23,25-pentaen-2-one
Canonical SMILES
CCCCC[C@H](C1[C@H](C[C@H](C[C@H](C[C@H](C[C@H](C[C@H](C[C@@H](/C(=C\\C=C\\C=C\\C=C\\C=C\\[C@@H]([C@H](OC1=O)C)O)/C)O)O)O)O)O)O)O)O
InChI
IMQSIXYSKPIGPD-YQRUMEKGSA-N
InChI Key
InChI=1S/C35H58O11/c1-4-5-11-16-31(42)34-33(44)22-29(40)20-27(38)18-25(36)17-26(37)19-28(39)21-32(43)23(2)14-12-9-7-6-8-10-13-15-30(41)24(3)46-35(34)45/h6-10,12-15,24-34,36-44H,4-5,11,16-22H2,1-3H3/b7-6+,10-8+,12-9+,15-13+,23-14+/t24-,25+,26-,27+,28-,29+,30+,31-,32+,33+,34-/m1/s1
Solubility
Soluble in methanol (up to 10 mg/ml)
Appearance
White or light yellow solid
Storage
Powder-20°C, 3 years; 4°C, 2 years; In solvent-80°C, 6 months; -20°C, 1 month.
Hazard Statements
Xi
Safety Description
26-36
Shipping
Room temperature
Source
Streptomyces miharaensis
Stability
Stable for 1 year from date of purchase as supplied. Solutions in methanol may be stored under ineRoom temperature gas at -20 °C for up to 2 months.
Storage Temperature
-20 °C
Supplemental Hazard Statements
H315-H319-H335
Symbol
GHS07
What is the molecular formula of Filipin III?

The molecular formula of Filipin III is C35H58O11.

What is the molecular weight of Filipin III?

The molecular weight of Filipin III is 654.8 g/mol.

What is the structure of Filipin III?

The structure of Filipin III is a macrolide with a polyol and olefinic compound.

Where is Filipin III found?

Filipin III is found in Streptomyces filipinensis.

What is the role of Filipin III?

Filipin III has a role as a bacterial metabolite and a fluorescent probe.

What are some synonyms for Filipin III?

Some synonyms for Filipin III are FILIPIN, Filimarisin, and 11078-21-0.

What is the IUPAC name of Filipin III?

The IUPAC name of Filipin III is (3R,4S,6S,8S,10R,12R,14R,16S,17E,19E,21E,23E,25E,27S,28R)-4,6,8,10,12,14,16,27-octahydroxy-3-[(1R)-1-hydroxyhexyl]-17,28-dimethyl-1-oxacyclooctacosa-17,19,21,23,25-pentaen-2-one.

What is the Canonical SMILES of Filipin III?

The Canonical SMILES of Filipin III is CCCCCC(C1C(CC(CC(CC(CC(CC(CC(C(=CC=CC=CC=CC=CC(C(OC1=O)C)O)C)O)O)O)O)O)O)O)O.

What is the InChIKey of Filipin III?

The InChIKey of Filipin III is IMQSIXYSKPIGPD-YQRUMEKGSA-N.

What is the CAS number of Filipin III?

The CAS number of Filipin III is 480-49-9.

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