DOTMA

• CAS: 104872-42-6
• Catalog Number: ACM104872426
• Category: Others
• Molecular Weight: 670.59
• Molecular Formula: C42H84ClNO2
• Description: DOTMA is one of the first cationic lipid used for gene transfection. DOTMA is an effective transfection agent in vitro and in vivo. DOTMA carries a positive charge on the surface of liposomes which condenses anionic nucleic acids and promotes efficient interactions between the cell membrane and the liposome.
• Synonyms: DOTMA; 1,2-di-O-octadecenyl-3-trimethylammonium propane
• IUPAC Name: N,N,N-trimethyl-2,3-bis(((Z)-octadec-9-en-1-yl)oxy)propan-1-aminium chloride
• Canonical SMILES: CCCCCCCC/C=C\CCCCCCCCOCC(OCCCCCCCC/C=C\CCCCCCCC)C[N+](C)(C)C.[Cl-]
• InChI: InChI=1S/C42H84NO2.ClH/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-44-41-42(40-43(3,4)5)45-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;/h20-23,42H,6-19,24-41H2,1-5H3;1H/q+1;/p-1/b22-20-,23-21-
• InChI Key: LDGWQMRUWMSZIU-LQDDAWAPSA-M
• Solubility: To be determined
• Appearance: Solid powder
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Alternative CAS: 717090-94-3 (cation);104872-42-6 (chloride)
• Drug Formulation: To be determined
• Elemental Analysis: C, 75.23; H, 12.63; Cl, 5.29; N, 2.09; O, 4.77
• Exact Mass: 669.6191
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stability: 1 Year
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).
• Storage Temperature: Dry, dark and at 0 - 4 °C for short term (days to weeks) or -20 °C for long term (months to years)