3,4-Dihydroxypyridine

• CAS: 10182-48-6
• Catalog Number: ACM10182486
• Category: Main Products
• Molecular Weight: 111.1
• Molecular Formula: C5H5NO2
• Description: 3,4-Dihydroxypyridine is a chemical compound with a structure consisting of a pyridine ring with hydroxyl groups (OH) attached at the 3rd and 4th positions. This compound is a derivative of pyridine and belongs to the class of heterocyclic compounds.
• Synonyms: 3,4-pyridinediol;3,4-DIHYDROXYPYRIDINE;3,4-DIHYDROXYPYRIDINE 99%;Pyridine-3,4-diol;pyridin-3,4-diol
• IUPAC Name: pyridine-3,4-diol
• Canonical SMILES: OC1=CC=NC=C1O
• InChI: 1S/C5H5NO2/c7-4-1-2-6-3-5(4)8/h1-3,8H,(H,6,7)
• InChI Key: ZCUUVWCJGRQCMZ-UHFFFAOYSA-N
• Boiling Point: 509.8±30.0 °C at 760 mmHg
• Flash Point: 262.1±24.6 °C
• Density: 1.4±0.1 g/mL
• Appearance: Brown solid
• Application: 3,4-Dihydroxypyridine is used in the synthesis of various pharmaceuticals and organic compounds. One of its important applications is in the production of the drug called L-DOPA (levodopa), which is used in the treatment of Parkinson's disease.
• Storage: Store at 0-8 °C
• Exact Mass: 111.032
• HTS Code: 2933399100
• MDL Number: MFCD01691806
• PSA: 53.35
• Refractive Index: 1.625
• Vapor Pressure: 0.0±1.4 mmHg at 25°C
• XLogP3: -1.25

Case Study

3,4-Dihydroxypyridine for Functionalization of Efficient Nanocatalysts

Veisi H,et al. RSC Adv., 2016,6, 27252-27259.

Magnetic Fe3O4 nanoparticles were functionalized with 3,4-dihydroxypyridine and then used as stable supports for palladium (Pd) to prepare reusable and efficient heterogeneous catalysts for catalyzing Suzuki cross-coupling reaction.
Synthesis procedure of high-efficiency catalyst Fe3O4/Py/Pd(0)
· The Fe3O4 MNPs powder (500 mg) was dispersed in 50 mL ethanol/water (volume ratio, 1 : 1) solution by sonication for 20 min, and 3,4-dihydroxypyridine (Py) (250 mg) was added to the mixture. The mixture was stirred for 5 h at 40 °C.
· The precipitated product was subjected to centrifugal separation, magnetic decantation separation and vacuum drying to obtain Fe3O4/Py compound.
· Fe3O4/Py (500 mg) was dispersed in CH3CN (30 mL) by ultrasonic bath. A solution of PdCl2 (30 mg) in 30 mL acetonitrile was added to the Fe3O4/Py dispersion for reaction.
· The obtained Fe3O4/Py/Pd(II) was separated by magnetic decantation and washed with CH3CN, H2O and acetone respectively.
· Reduction of Fe3O4/Py/Pd(II) with sodium borohydride. The final product Fe3O4/Py/Pd(0) was washed with water and ethanol and dried under vacuum at 40°C.

Custom Q&A

What is the molecular formula of 3,4-Dihydroxypyridine?

The molecular formula of 3,4-Dihydroxypyridine is C5H5NO2.

What is the molecular weight of 3,4-Dihydroxypyridine?

The molecular weight of 3,4-Dihydroxypyridine is 111.10 g/mol.

Is 3,4-Dihydroxypyridine a natural product?

Yes, 3,4-Dihydroxypyridine is a natural product found in Cortinarius rubellus.

What is the IUPAC name of 3,4-Dihydroxypyridine?

The IUPAC name of 3,4-Dihydroxypyridine is 3-hydroxy-1H-pyridin-4-one.

What is the InChI of 3,4-Dihydroxypyridine?

The InChI of 3,4-Dihydroxypyridine is InChI=1S/C5H5NO2/c7-4-1-2-6-3-5(4)8/h1-3,8H,(H,6,7).

What is the InChIKey of 3,4-Dihydroxypyridine?

The InChIKey of 3,4-Dihydroxypyridine is ZCUUVWCJGRQCMZ-UHFFFAOYSA-N.

How many hydrogen bond donor counts does 3,4-Dihydroxypyridine have?

3,4-Dihydroxypyridine has 2 hydrogen bond donor counts.

How many hydrogen bond acceptor counts does 3,4-Dihydroxypyridine have?

3,4-Dihydroxypyridine has 3 hydrogen bond acceptor counts.

What is the topological polar surface area of 3,4-Dihydroxypyridine?

The topological polar surface area of 3,4-Dihydroxypyridine is 49.3Ų.

How many heavy atoms are there in 3,4-Dihydroxypyridine?

There are 8 heavy atoms in 3,4-Dihydroxypyridine.