4,5-Dicaffeoylquinic acid

• CAS: 57378-72-0
• Catalog Number: ACM57378720-1
• Category: Inhibitors
• Molecular Weight: 516.45
• Molecular Formula: C25H24O12
• Description: 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) is an antioxidant, can be isolated from Gynura divaricata and Laggera alata. 4,5-Dicaffeoylquinic acid reduces islet cell apoptosis and improves pancreatic function in type 2 diabetic mice, and has obvious inhibitory activities against yeast α-glucosidase. 4,5-Dicaffeoylquinic acid inhibits prostate cancer cells through cell cycle arrest. 4,5-Dicaffeoylquinic acid also has anti-apoptotic, anti-injury and anti-hepatitis B virus effects.
• Synonyms: Isochlorogenic acid C
• IUPAC Name: (1R,3R,4S,5R)-3,4-bis[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]-1,5-dihydroxycyclohexane-1-carboxylic acid
• Canonical SMILES: C1[C@H]([C@@H]([C@@H](C[C@]1(C(=O)O)O)OC(=O)/C=C/C2=CC(=C(C=C2)O)O)OC(=O)/C=C/C3=CC(=C(C=C3)O)O)O
• InChI: InChI=1S/C25H24O12/c26-15-5-1-13(9-17(15)28)3-7-21(31)36-20-12-25(35,24(33)34)11-19(30)23(20)37-22(32)8-4-14-2-6-16(27)18(29)10-14/h1-10,19-20,23,26-30,35H,11-12H2,(H,33,34)/b7-3+,8-4+/t19-,20-,23+,25-/m1/s1
• InChI Key: UFCLZKMFXSILNL-RVXRWRFUSA-N
• Boiling Point: 810.8±65.0 °C
• Appearance: Powder
• pKa: 3.70±0.50

Synthetic Use

Downstream Synthesis Route 1

• 327-97-9

• 32719-11-2
• 1258222-08-0
• 1258222-09-1
• 331-39-5
• 77-95-2
• 905-99-7
• 14534-61-3
• 202650-88-2

Reference: [1]Journal of Agricultural and Food Chemistry,2010,vol. 58,p. 12578 - 12584

* For details of the synthesis route, please refer to the original source to ensure accuracy.