2,8-Diaza-spiro[4.5]decane-2-carboxylic acid tert-butyl ester

• CAS: 336191-17-4
• Catalog Number: ACM336191174
• Category: Other Products
• Molecular Weight: 240.3448
• Molecular Formula: C13H24N2O2
• Synonyms: 2,8-DIAZA-SPIRO[4.5]DECANE-2-CARBOXYLIC ACID TERT-BUTYL ESTER;TERT-BUTYL 2,8-DIAZASPIRO[4.5]DECANE-2-CARBOXYLATE;2-Boc-2,8-Diaza-spiro[4.5]decane;tert-Butyl2,7-diazaspiro[4,5]decane-2-carboxylate,98%
• IUPAC Name: tert-butyl 2,8-diazaspiro[4.5]decane-2-carboxylate
• Canonical SMILES: CC(C)(C)OC(=O)N1CCC2(C1)CCNCC2
• InChI Key: NFNCPNAVNRBDOU-UHFFFAOYSA-N
• Boiling Point: 360.1ºC at 760 mmHg
• Flash Point: 170.8ºC
• Density: 1.07g/cm³
• Exact Mass: 240.18400
• H-Bond Acceptor: 3
• H-Bond Donor: 1
• MDL Number: MFCD06739056
• Size: 100mg,250mg,500mg,1g,5g,25g

Synthetic Use

Upstream Synthesis Route 1

• 929301-98-4

• 336191-17-4

Reference: [1] Patent: WO2007/30061, 2007, A1, . Location in patent: Page/Page column 88; 89

Upstream Synthesis Route 2

• 336191-16-3

• 336191-17-4

Reference: [1] Bioorganic and Medicinal Chemistry Letters, 2002, vol. 12, # 7, p. 1103 - 1107
[2] Patent: US2008/247964, 2008, A1, . Location in patent: Page/Page column 35
[3] Patent: WO2004/69256, 2004, A1, . Location in patent: Page/Page column 42
[4] Patent: WO2007/140383, 2007, A2, . Location in patent: Page/Page column 55

Upstream Synthesis Route 3

• 336191-15-2

• 336191-17-4

Reference: [1] Bioorganic and Medicinal Chemistry Letters, 2002, vol. 12, # 7, p. 1103 - 1107
[2] Patent: WO2007/140383, 2007, A2,

Upstream Synthesis Route 4

• 34702-66-4

• 336191-17-4

Reference: [1]Bioorganic and Medicinal Chemistry Letters,2002,vol. 12,p. 1103 - 1107

Upstream Synthesis Route 5

• 3612-20-2

• 336191-17-4

Reference: [1]Bioorganic and Medicinal Chemistry Letters,2002,vol. 12,p. 1103 - 1107

Downstream Synthesis Route 1

• 1191-95-3
• 336191-17-4

• 1001054-52-9

Reference: [1]Patent: US2008/247964,2008,A1 .Location in patent: Page/Page column 35

* For details of the synthesis route, please refer to the original source to ensure accuracy.