Deoxyshikonin

• CAS: 43043-74-9
• Catalog Number: ACM43043749
• Category: Inhibitors
• Molecular Weight: 272.30
• Molecular Formula: C16H16O4
• Description: Deoxyshikonin is isolated from Arnebia euchroma with antitumor activity. Deoxyshikonin increases the expression of VEGF-C and VEGF-A mRNA in HMVEC-dLy, promotes HIF-1α and HIF-1β subunit interaction and binds to specific DNA sequences targeted by HIF, indicates a prolymphangiogenesis as well as a proangiogenesis effect in vitro. Deoxyshikonin shows significant synergic antimicrobial activity against S. pneumonia (MIC=17 μg/mL), also shows significantly inhibitory activities against MRSA.
• Canonical SMILES: O=C1C(CC/C=C(C)/C)=CC(C2=C1C(O)=CC=C2O)=O
• Appearance: Solid
• Storage: 4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light).
• Shipping: Can be shipped at room temperature, where not in use may vary.
• Source: PlantsBoraginaceaeArnebia euchroma (Royle) Johnst.