DEL22379

• CAS: 1693734-80-3
• Catalog Number: ACM1693734803
• Category: Inhibitors
• Molecular Weight: 444.53
• Molecular Formula: C26H28N4O3
• Description: DEL22379, also known as NPX800, is ERK dimerization inhibitor. DEL-22379 has been reported to inhibit ERK dimerization which was unaffected by drug-resistant mechanism reactivating the ERK signaling.
• Synonyms: DEL22379; DEL-22379; DEL 22379; NPX800; NPX 800; NPX-800
• IUPAC Name: N-[2,3-Dihydro-3-[(5-methoxy-1H-indol-3-yl)methylene]-2-oxo-1H-indol-5-yl]-1-piperidinepropanamide
• Canonical SMILES: O=C(NC1=CC2=C(NC(/C2=C/C3=CNC4=C3C=C(OC)C=C4)=O)C=C1)CCN5CCCCC5
• InChI: InChI=1S/C26H28N4O3/c1-33-19-6-8-23-20(15-19)17(16-27-23)13-22-21-14-18(5-7-24(21)29-26(22)32)28-25(31)9-12-30-10-3-2-4-11-30/h5-8,13-16,27H,2-4,9-12H2,1H3,(H,28,31)(H,29,32)/b22-13+
• InChI Key: INQUULPXCZAKMS-LPYMAVHISA-N
• Solubility: To be determined
• Appearance: To be determined
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Alternative CAS: 1693734-80-3 (EZ mixture); 786620-82-4 (E-isomer); 710275-80-2 (Z-isomer); 181222-54-8 (Z-isomer HCl); 181222-52-6 (E-isomer HCl)
• Drug Formulation: To be determined
• Elemental Analysis: C, 70.25; H, 6.35; N, 12.60; O, 10.80
• Exact Mass: 444.2161
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).