Corydine

• CAS: 476-69-7
• Catalog Number: ACM476697
• Category: Inhibitors
• Molecular Weight: 341.4
• Molecular Formula: C₂₀H₂₃NO₄
• Description: Corydine is a naturally occurring alkaloid which can be extracted from plants such as Croton echinocarpus leaves. Corydine is efficient on inhibiting reverse transcriptase (RT) activity with an IC50 of 356.8 μg/mL. Corydine displays significant in vitro anti-HIV potential, inhibiting 40% of the HIV-1 reverse transcriptase enzyme activity at a concentration of 450 μg/mL of Corydine.
• Synonyms: Glaucentrine
• InChI: InChI=1S/C20H23NO4/c1-21-8-7-12-10-15(24-3)19(22)18-16(12)13(21)9-11-5-6-14(23-2)20(25-4)17(11)18/h5-6,10,13,22H,7-9H2,1-4H3/t13-/m0/s1
• InChI Key: IDQUPXZJURZAGF-ZDUSSCGKSA-N
• Melting Point: 165-167 °C
• Complexity: 475
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Exact Mass: 341.16270821
• Heavy Atom Count: 25
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 1
• Isomeric SMILES: CN1CCC2=CC(=C(C3=C2[C@@H]1CC4=C3C(=C(C=C4)OC)OC)O)OC
• Monoisotopic Mass: 341.16270821
• Physical State: Powder
• Rotatable Bond Count: 3
• Topological Polar Surface Area: 51.2 Ų