BTB06584

• CAS: 219793-45-0
• Catalog Number: ACM219793450
• Category: Inhibitors
• Molecular Weight: 417.82
• Molecular Formula: C19H12ClNO6S
• Description: BTB06584 is an IF1 -dependent selective inhibitor of the mitochondrial F1 Fo-ATPase. BTB06584 inhibited F1 Fo-ATPase activity with no effect on ΔΨm or O2 consumption. BTB06584 efficiency was increased by IF1 overexpression and reduced by silencing the protein.BTB06584 may represent a valuable tool to selectively inhibit mitochondrial F1 Fo-ATPase activity without compromising ATP synthesis and to limit ischaemia-induced injury caused by reversal of the mitochondrial F1 Fo-ATPsynthase.
• Synonyms: BTB06584; BTB-06584; BTB 06584
• IUPAC Name: 2-nitro-5-(phenylsulfonyl)phenyl 4-chlorobenzoate
• Canonical SMILES: O=S(C1=CC(OC(C2=CC=C(Cl)C=C2)=O)=C([N+]([O-])=O)C=C1)(C3=CC=CC=C3)=O
• InChI: InChI=1S/C19H12ClNO6S/c20-14-8-6-13(7-9-14)19(22)27-18-12-16(10-11-17(18)21(23)24)28(25,26)15-4-2-1-3-5-15/h1-12H
• InChI Key: WNDWKKPBLAKXMI-UHFFFAOYSA-N
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Drug Formulation: This drug may be formulated in DMSO
• Elemental Analysis: C, 54.62; H, 2.90; Cl, 8.48; N, 3.35; O, 22.98; S, 7.67
• Exact Mass: 417.0074
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).