Bryostatin 1

• CAS: 83314-01-6
• Catalog Number: ACM83314016
• Category: Inhibitors
• Molecular Weight: 905.03
• Molecular Formula: C₄₇H₆₈O₁₇
• Description: Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a potent and central nervous system (CNS)-permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein with Kis of 8.07 nM and 0.45 nM, respectively. Bryostatin 1 has anti-cancer, anti-inflammatory, neuroprotective, anti-HIV-1 infection properties.
• Synonyms: BRYOSTATIN 1;BRYO 1;2,4-Octadienoic acid, (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(acetyloxy)-1,11,21-trihydroxy-17-(1R)-1-hydroxyethyl-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo21.3.1.13,7.111,15nonacos-8-en;BRYOSTATIN;bryostatin1,0;(26R)-Bryostatin 1;NSC-339555;(1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(Acetyloxy)-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-12-yl2,4-octadienoicacidester
• Appearance: solid
• Hazard Statements: Xn
• Safety Description: 22-24/25-36/37

Custom Q&A

What is the molecular formula of Bryostatin 1?

The molecular formula of Bryostatin 1 is C47H68O17.

What is the molecular weight of Bryostatin 1?

The molecular weight of Bryostatin 1 is 905.0 g/mol.

What is the IUPAC name of Bryostatin 1?

The IUPAC name of Bryostatin 1 is [(1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-acetyloxy-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.1 3,7 .1 11,15 ]nonacos-8-en-12-yl] (2E,4E)-octa-2,4-dienoate.

What is the InChI key of Bryostatin 1?

The InChI key of Bryostatin 1 is MJQUEDHRCUIRLF-TVIXENOKSA-N.

What is the canonical SMILES of Bryostatin 1?

The canonical SMILES of Bryostatin 1 is CCCC=CC=CC(=O)OC1C(=CC(=O)OC)CC2CC(OC(=O)CC(CC3CC(C(C(O3)(CC4CC(=CC(=O)OC)CC(O4)C=CC(C1(O2)O)(C)C)O)(C)C)OC(=O)C)O)C(C)O.

What is the CAS number of Bryostatin 1?

The CAS number of Bryostatin 1 is 83314-01-6.

What is the ChEMBL ID of Bryostatin 1?

The ChEMBL ID of Bryostatin 1 is CHEMBL449158.

What is the UNII of Bryostatin 1?

The UNII of Bryostatin 1 is 37O2X55Y9E.

What is the NCI Thesaurus code of Bryostatin 1?

The NCI Thesaurus code of Bryostatin 1 is C1026.

What is the Wikipedia page for Bryostatin?

The Wikipedia page for Bryostatin can be found under the same name.