Boc-Hyp-OH (cryst)

• CAS: 13726-69-7
• Catalog Number: ACM13726697-1
• Category: Amino Acids
• Molecular Weight: 231.25
• Description: Building block for introduction of hydroxyproline amino-acid residues by Boc SPPS.
• Synonyms: Boc-Hyp-OH (cryst), N-α-t.-Boc-L-trans-4-hydroxyproline
• InChI: 1S/C10H17NO5/c1-10(2,3)16-9(15)11-5-6(12)4-7(11)8(13)14/h6-7,12H,4-5H2,1-3H3,(H,13,14)
• InChI Key: BENKAPCDIOILGV-UHFFFAOYSA-N
• Melting Point: 122 ℃(decomposition)
• Application: Peptide synthesis.
• Assay: ≥97% (TLC)
• Form: powder
• Functional Group: hydroxyl
• MDL Number: MFCD00053370
• Quality Level: 200
• Reaction Suitability: reaction type: Boc solid-phase peptide synthesis
• Storage Temperature: 2-30℃

Synthetic Use

Downstream Synthesis Route 1

• 64-17-5
• 13726-69-7

• 37813-30-2

Reference: [1] Bioorganic and Medicinal Chemistry Letters, 2000, vol. 10, # 14, p. 1511 - 1514
[2] Patent: US2005/165065, 2005, A1, . Location in patent: Page/Page column 21

Downstream Synthesis Route 2

• 74-96-4
• 13726-69-7

• 37813-30-2

Reference: [1] Chemistry Letters, 2006, vol. 35, # 3, p. 300 - 301
[2] Chemistry Letters, 2001, # 7, p. 634 - 635

Downstream Synthesis Route 3

• 13726-69-7
• 75-03-6

• 37813-30-2

Reference: [1] Patent: WO2004/76407, 2004, A2, . Location in patent: Page 27-29

Downstream Synthesis Route 4

• 100-39-0
• 13726-69-7

• 40350-83-2

Reference: [1]European Journal of Organic Chemistry,2014,vol. 2014,p. 5351 - 5355

Downstream Synthesis Route 5

• 13726-69-7

• 61478-26-0

Reference: [1]Patent: US2005/239826,2005,A1 .Location in patent: Page/Page column 27

Downstream Synthesis Route 6

• 13726-69-7

• 84348-37-8

Reference: [1]Patent: WO2015/19238,2015,A1 .Location in patent: Page/Page column 9

* For details of the synthesis route, please refer to the original source to ensure accuracy.