Specification
Description
Azido-PEG5-alcohol is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
1-Azidohexaethylene glycol
IUPAC Name
2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethanol
Canonical SMILES
C(COCCOCCOCCOCCO)N=[N+]=[N-]
InChI
InChI=1S/C10H21N3O5/c11-13-12-1-3-15-5-7-17-9-10-18-8-6-16-4-2-14/h14H,1-10H2
InChI Key
JTGGTGKXQQGEHB-UHFFFAOYSA-N
Solubility
Slightly soluble in chloroform and methanol
Covalently-Bonded Unit Count
1
Monoisotopic Mass
263.14812078
Refractive Index
n20/D 1.465-1.469(lit.)
Topological Polar Surface Area
71.5 Ų
Type
Bioorthogonal Reagents