Structure

Auranofin

CAS
34031-32-8
Catalog Number
ACM34031328
Category
Inhibitors
Molecular Weight
678.48
Molecular Formula
C20H34AuO9PS

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Specification

Description
Auranofin (SKF-39162) is a thioredoxin reductase (TrxR) inhibitor with an IC50 of 0.2 μM. Auranofin exhibits antiviral activity against SARS-CoV21, with a CC50 of 4.2 μM for monkey kidney Vero E6 cells.
Canonical SMILES
CC(O[C@@H]1[C@@H](OC(C)=O)[C@H]([SH-][Au+]P(CC)(CC)CC)O[C@H](COC(C)=O)[C@H]1OC(C)=O)=O
Appearance
Solid
Storage
4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture).
Shipping
Can be shipped at room temperature, where not in use may vary.
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