Arteannuin B

CAS
50906-56-4
Catalog Number
ACM50906564
Category
Inhibitors
Molecular Weight
248.3
Molecular Formula
C15H20O3

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Specification

Description
Arteannuin B co-occurs with artemisinin, which is the potent antimalarial principle of the Chinese medicinal herb Artemisia annua (Asteraceae). Arteannuin B shows anti-SARS-CoV-2 potential with an EC50 of 10.28 μM.
Canonical SMILES
CC1CCC2C(=C)C(=O)OC23C1CCC4(C3O4)C
InChI Key
QWQSMEDUZQDVLA-USPGQWGOSA-N
Appearance
Powder
Storage
4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light).
Shipping
Can be shipped at room temperature, where not in use may vary.
Source
PlantsLeguminosaeSophora macrocarpa Sm.PlantsCompositae

Upstream Synthesis Route 1

  • 80286-58-4
  • 63968-64-9
  • 50906-56-4

Reference: [1]Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry,1992,vol. 31,p. 880 - 882

Downstream Synthesis Route 1

  • 50906-56-4
  • 64390-16-5

Reference: [1]Bhattacharya, Asish K.; Pal, Mahesh; Jain, Dharam C.; Joshi, Bhawani S.; Roy, Raja; Rychlewska, Urszula; Sharma, Ram P.
[Tetrahedron, 2003, vol. 59, # 16, p. 2871 - 2876]
[2]Bhattacharya, Asish K.; Jain, Dharam C.; Sharma, Ram P.; Roy, Raja; McPhail, Andrew T.
[Tetrahedron, 1997, vol. 53, # 44, p. 14975 - 14990]
[3]Bhattacharya, Asish K.; Jain, Dharam C.; Sharma, Ram P.
[Journal of Chemical Research - Part S, 1998, # 12, p. 768 - 769]
[4]Bhattacharya, Asish K.; Jain, Dharam C.; Sharma, Ram P.
[Journal of Chemical Research - Part S, 1998, # 12, p. 768 - 769]

* For details of the synthesis route, please refer to the original source to ensure accuracy.

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