Arborinine

• CAS: 5489-57-6
• Catalog Number: ACM5489576
• Category: Inhibitors
• Molecular Weight: 285.29
• Description: Arborinine is a potent and orally activeLSD1 inhibitor. Arborinine increases the expression of H3K4me1/2, H3K9me1/2, E-cad protein and decreases the expression of UBE2O protein level. Arborinine induces cell cycle arrest at S phase. Arborinine shows antitumor activity .
• Synonyms: 1-Hydroxy-2,3-dimethoxy-10-methylacridin-9(10H)-one
• InChI: InChI=1S/C16H15NO4/c1-17-10-7-5-4-6-9(10)14(18)13-11(17)8-12(20-2)16(21-3)15(13)19/h4-8,19H,1-3H3
• InChI Key: ATBZZQPALSPNMF-UHFFFAOYSA-N
• Melting Point: 177-177.5 °C
• Complexity: 402
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 0
• Exact Mass: 285.10010796
• Heavy Atom Count: 21
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 1
• Monoisotopic Mass: 285.10010796
• Physical State: Oil
• Rotatable Bond Count: 2
• Topological Polar Surface Area: 59 Ų