A22 hydrochloride

• CAS: 22816-60-0
• Catalog Number: ACM22816600-1
• Category: Inhibitors
• Molecular Weight: 271.58
• Molecular Formula: C8H9Cl3N2S
• Description: A22 is an inhibitor of MreB, an actin-like bacterial protein, and has been shown to act as an antiobiotic adjuvant. A22 inhibition of MreB disrupts the bacterial actin cytoskeleton, which can cause an increase in cell permeability and altered transport.
• Synonyms: MreB Perturbing Compound A22; A22 hydrochloride
• IUPAC Name: S-(3,4-Dichlorobenzyl)isothiourea hydrochloride
• Canonical SMILES: N=C(N)SCC1=CC=C(Cl)C(Cl)=C1.[H]Cl
• InChI: InChI=1S/C8H8Cl2N2S.ClH/c9-6-2-1-5(3-7(6)10)4-13-8(11)12;/h1-3H,4H2,(H3,11,12);1H
• InChI Key: VBJNMXMOMSWRDV-UHFFFAOYSA-N
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Alternative CAS: 22816-60-0 (HCl); 22297-13-8 (free base)
• Drug Formulation: This drug may be formulated in DMSO
• Elemental Analysis: C, 35.38; H, 3.34; Cl, 39.16; N, 10.32; S, 11.80
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).