7-Bromoquinazolin-4(3H)-one

• CAS: 194851-16-6
• Catalog Number: ACM194851166
• Category: Bromine Series
• Molecular Weight: 225.04
• Molecular Formula: C8H5BrN2O
• Synonyms: 7-BROMO-1H-QUINAZOLIN-4-ONE;7-BROMO-3,4-DIHYDROQUINAZOLIN-4-ONE;7-BROMOQUINAZOLIN-4(3H)-ONE
• IUPAC Name: 7-bromo-1H-quinazolin-4-one
• Canonical SMILES: C1=CC2=C(C=C1Br)NC=NC2=O
• InChI Key: FUGKKMYSCAYXJJ-UHFFFAOYSA-N
• Boiling Point: 428.8ºC at 760 mmHg
• Flash Point: 213.1ºC
• Density: 1.82 g/cm³
• Exact Mass: 223.95900
• H-Bond Acceptor: 1
• H-Bond Donor: 1

Synthetic Use

Upstream Synthesis Route 1

• 20776-50-5
• 77287-34-4

• 194851-16-6

Reference: [1] Patent: US2013/12489, 2013, A1, . Location in patent: Paragraph 0182

Upstream Synthesis Route 2

• 112253-70-0
• 122-51-0

• 194851-16-6

Reference: [1] Patent: WO2008/23161, 2008, A1, . Location in patent: Page/Page column 119-120

Upstream Synthesis Route 3

• 67-56-1
• 112253-70-0

• 194851-16-6

Reference: [1] Organic Letters, 2016, vol. 18, # 11, p. 2580 - 2583
[2] Patent: CN107337646, 2017, A, . Location in patent: Paragraph 0085; 0086; 0087; 0088

Upstream Synthesis Route 4

• 112253-70-0
• 122-51-0

• 194851-16-6

Reference: [1]Patent: WO2008/23161,2008,A1 .Location in patent: Page/Page column 119-120