5-Chloro Benzothiophene

• CAS: 20532-33-6
• Catalog Number: ACM20532336
• Category: Other Products
• Molecular Weight: 168.64
• Molecular Formula: C8H5ClS
• Synonyms: 5-CHLOROBENZOTHIOPHENE;5-Chlorobenzo[b]thiophene;5-chlorine Benzothiophene;5-Chlorobenzothiophene ,98%;5-Chlorothionaphthene
• IUPAC Name: 5-chloro-1-benzothiophene
• Canonical SMILES: C1=CC2=C(C=CS2)C=C1Cl
• InChI Key: SNYURIHMNFPQFL-UHFFFAOYSA-N
• Boiling Point: 261.5ºC at 760 mmHg
• Flash Point: 147.6ºC
• Density: 1.349 g/cm³
• Exact Mass: 167.98000
• H-Bond Acceptor: 1
• H-Bond Donor: 0

Synthetic Use

Upstream Synthesis Route 1

• 50548-46-4

• 20532-33-6

Reference: [1] Patent: US2008/21026, 2008, A1, . Location in patent: Page/Page column 17; 27

Upstream Synthesis Route 2

• 110-81-6
• 106-46-7

• 188290-36-0
• 20532-33-6
• 5181-10-2
• 108-90-7
• 106-54-7

Reference: [1]Journal of Heterocyclic Chemistry,1988,vol. 25,p. 1271 - 1272
[2]MedChemComm,2016,vol. 7,p. 1093 - 1101
[3]Proceedings - Indian Academy of Sciences, Section A,1950,p. 396,401
[4]Patent: WO2013/119895,2013,A1 .Location in patent: Paragraph 00291

Upstream Synthesis Route 3

• 50548-46-4

• 20532-33-6

Reference: [1]Patent: US2008/21026,2008,A1 .Location in patent: Page/Page column 17; 27

Downstream Synthesis Route 1

• 20532-33-6

• 20532-28-9

Reference: [1] Organic Letters, 2013, vol. 15, # 14, p. 3734 - 3737
[2] Angewandte Chemie - International Edition, 2015, vol. 54, # 12, p. 3773 - 3777[3] Angew. Chem., 2015, vol. 127, # 12, p. 3844 - 3848,5
[4] Organic Letters, 2014, vol. 16, # 17, p. 4388 - 4391
[5] Organometallics, 2016, vol. 35, # 18, p. 3248 - 3254

Downstream Synthesis Route 2

• 20532-33-6

• 19301-35-0

Reference: [1] Journal of Organic Chemistry, 2014, vol. 79, # 11, p. 5351 - 5358

* For details of the synthesis route, please refer to the original source to ensure accuracy.