4-Chloro-2-(methylthio)pyrimidine-5-carboxylic acid

• CAS: 74840-34-9
• Catalog Number: ACM74840349
• Category: Other Products
• Molecular Weight: 204.6370
• Molecular Formula: C₆H₅ClN₂O₂S
• Synonyms: 4-Chloro-2-(methylthio)pyrimidine-5-carboxylic acid
• IUPAC Name: 4-chloro-2-methylsulfanylpyrimidine-5-carboxylic acid
• Canonical SMILES: CSC1=NC=C(C(=N1)Cl)C(=O)O
• InChI Key: MYNMNRVNVCHWIT-UHFFFAOYSA-N
• Boiling Point: 380.91ºC at 760 mmHg
• Flash Point: 184.168ºC
• Density: 1.597g/cm³
• Exact Mass: 203.97600
• H-Bond Acceptor: 4
• H-Bond Donor: 1

Synthetic Use

Upstream Synthesis Route 1

• 5909-24-0

• 74840-34-9

Reference: [1] MedChemComm, 2015, vol. 6, # 9, p. 1693 - 1697
[2] Patent: US2008/114007, 2008, A1, . Location in patent: Page/Page column 82

Upstream Synthesis Route 2

• 5909-24-0

• 74840-34-9

Reference: [1]Bioorganic and Medicinal Chemistry Letters,2019,vol. 29,p. 1481 - 1486
[2]MedChemComm,2015,vol. 6,p. 1693 - 1697
[3]Patent: US2008/114007,2008,A1 .Location in patent: Page/Page column 82

Downstream Synthesis Route 1

• 74840-34-9

• 55084-66-7

Reference: [1] Patent: CN107312012, 2017, A, . Location in patent: Paragraph 0026-0027

Downstream Synthesis Route 2

• 74840-34-9

• 66116-82-3

Reference: [1] MedChemComm, 2015, vol. 6, # 9, p. 1693 - 1697

Downstream Synthesis Route 3

• 74840-34-9

• 66206-82-4

Reference: [1]Patent: US2008/114007,2008,A1 .Location in patent: Page/Page column 82

* For details of the synthesis route, please refer to the original source to ensure accuracy.