3-OXO-3,4-DIHYDRO-QUINOXALINE-2-CARBOXYLIC ACID

• CAS: 36818-07-2
• Catalog Number: ACM36818072
• Category: Other Products
• Molecular Weight: 190.16
• Molecular Formula: C9H6N2O3
• Synonyms: CBMicro_008493, NCIOpen2_002913, Oprea1_061260, Oprea1_540401, Oprea1_668853, CBDivE_006184, NSC65995, STK503405, ALBB-005429, CID248643, ethyl 3-hydroxyquinoxaline-2-carboxylate, ZINC08622307, BIM-0008324.P001, 36818-07-2
• IUPAC Name: ethyl 3-oxo-4H-quinoxaline-2-carboxylate
• Canonical SMILES: CCOC(=O)C1=NC2=CC=CC=C2NC1=O
• InChI Key: MIIFHRBUBUHJMC-UHFFFAOYSA-N
• Boiling Point: 371.9ºC at 760mmHg
• Flash Point: 178.7ºC
• Density: 1.34g/cm³
• Exact Mass: 218.06900
• H-Bond Acceptor: 4
• H-Bond Donor: 1

Synthetic Use

Downstream Synthesis Route 1

• 36818-07-2

• 5424-05-5

Reference: [1] Journal of the Chemical Society, 1945, p. 622,625

Downstream Synthesis Route 2

• 36818-07-2

• 1448-87-9

Reference: [1] Journal of the Chemical Society, 1945, p. 622,625

Downstream Synthesis Route 3

• 36818-07-2

• 20254-76-6

Reference: [1] Journal of the Chemical Society, 1945, p. 622,625
[2] Zhurnal Obshchei Khimii, 1955, vol. 25, p. 161,163; engl. Ausg. S. 145, 147
[3] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 4, p. 1253 - 1256
[4] Archiv der Pharmazie, 2012, vol. 345, # 9, p. 687 - 694

Downstream Synthesis Route 4

• 36818-07-2

• 1204-75-7

Reference: [1]Obafemi, Craig A.; Pfleiderer, Wolfgang
[Helvetica Chimica Acta, 1994, vol. 77, # 6, p. 1549 - 1556]
[2]Sanna, Paolo; Carta, Antonio; Loriga, Mario; Zanetti, Stefania; Sechi, Leonardo
[Il Farmaco, 1998, vol. 53, # 7, p. 455 - 461]
[3]Gowenlock et al.
[Journal of the Chemical Society, 1945, p. 622,625]
[4]Sanna, Paolo; Carta, Antonio; Loriga, Mario; Zanetti, Stefania; Sechi, Leonardo
[Il Farmaco, 1998, vol. 53, # 7, p. 455 - 461]

Downstream Synthesis Route 5

• 36818-07-2

• 90323-01-6

Reference: [1]Yoshida, Kei; Otomasu, Hirotaka
[Chemical and pharmaceutical bulletin, 1984, vol. 32, # 9, p. 3361 - 3365]
[2]Clark-Lewis
[Journal of the Chemical Society, 1957, p. 422,426]
King; Clark-Lewis
[Journal of the Chemical Society, 1953, p. 172,176]

Downstream Synthesis Route 6

• 36818-07-2

• 49679-45-0

Reference: [1]European Journal of Medicinal Chemistry,2018,vol. 154,p. 101 - 109

* For details of the synthesis route, please refer to the original source to ensure accuracy.