2-Aminopyrimidine-5-boronic acid, pinacol ester

• CAS: 402960-38-7
• Catalog Number: ACM402960387
• Category: Boronic Esters
• Molecular Weight: 221.06
• Molecular Formula: C₁₀H₁₆BN₃O₂
• Synonyms: 2-AMINO-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIMIDINE;2-AMINOPYRIMIDINE-5-BORONIC ACID, PINACOL ESTER;5-METHOXYTHIOPHENE-2-BORONIC ACID;5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine;(2-Aminopyrimidin-5-yl)boronic acid pinaco
• IUPAC Name: 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine
• Canonical SMILES: B1(OC(C(O1)(C)C)(C)C)C2=CN=C(N=C2)N
• InChI Key: BPQVMIDUTRJYSC-UHFFFAOYSA-N
• Boiling Point: 394.8ºC at 760 mmHg
• Melting Point: 209-211ºC
• Flash Point: 192.6ºC
• Density: 1.13 g/cm³
• Exact Mass: 221.13400
• Hazard Statements: Xi
• H-Bond Acceptor: 5
• H-Bond Donor: 1
• Safety Description: 26-36/39

Synthetic Use

Upstream Synthesis Route 1

• 7752-82-1
• 73183-34-3

• 402960-38-7

Reference: [1] Patent: KR2016/38598, 2016, A, . Location in patent: Paragraph 0111; 0112

Upstream Synthesis Route 2

• 76-09-5
• 121-43-7
• 1072850-89-5

• 402960-38-7

Reference: [1] Patent: US2008/269523, 2008, A1, . Location in patent: Page/Page column 7

Upstream Synthesis Route 3

• 7752-82-1
• 73183-34-3

• 402960-38-7

Reference: [1]Patent: KR2016/38598,2016,A .Location in patent: Paragraph 0111; 0112

Downstream Synthesis Route 1

• 402960-38-7
• 19957-47-2

• 31408-17-0

Reference: [1] Chemical Communications, 2013, vol. 49, # 46, p. 5268 - 5270

Downstream Synthesis Route 2

• 10397-13-4
• 402960-38-7

• 944401-22-3

Reference: [1]Molecules,2018,vol. 23,p. 1 - 13
[2]Patent: WO2007/84786,2007,A1 .Location in patent: Page/Page column 128-129

* For details of the synthesis route, please refer to the original source to ensure accuracy.