2,5-Anhydro-D-mannitol

• CAS: 41107-82-8
• Catalog Number: ACM41107828
• Category: Other Products
• Molecular Weight: 164.16
• Molecular Formula: C6H12O5
• Synonyms: 2-Deoxy-β-D-fructofuranose
• IUPAC Name: (2R,3S,4S,5R)-2,5-bis(hydroxymethyl)oxolane-3,4-diol
• Canonical SMILES: C([C@@H]1[C@H]([C@@H]([C@H](O1)CO)O)O)O
• InChI: InChI=1S/C6H12O5/c7-1-3-5(9)6(10)4(2-8)11-3/h3-10H,1-2H2/t3-,4-,5-,6-/m1/s1
• InChI Key: MCHWWJLLPNDHGL-KVTDHHQDSA-N
• Boiling Point: 211.61 °C
• Melting Point: 101-103 °C (lit.)
• Density: 1.17 g/ml
• Appearance: White to off-white solid
• pKa: 13.26±0.70
• Solubility In Water: Slightly

Synthetic Use

Upstream Synthesis Route 1

• 69-65-8

• 641-74-7
• 7726-97-8
• 492-93-3
• 41107-82-8

Reference: [1] Synthesis, 1994, # 10, p. 1087 - 1090

Upstream Synthesis Route 2

• 495-75-0

• 41107-82-8

Reference: [1]Bendiak, Brad; Salayan, Mary E.; Pantoja, Mario
[Journal of Organic Chemistry, 1995, vol. 60, # 25, p. 8245 - 8256]

Downstream Synthesis Route 1

• 76-83-5
• 41107-82-8

• 68774-47-0

Reference: [1]Takahashi, Shunya; Fujisawa, Kenji; Sakairi, Nobuo; Nakata, Tadashi
[Heterocycles, 2000, vol. 53, # 6, p. 1361 - 1370]

Downstream Synthesis Route 2

• 98-59-9
• 41107-82-8

• 84447-05-2

Reference: [1]Current Patent Assignee: LANXESS AG - EP1400527, 2004, A1
Location in patent: Page 16
[2]Current Patent Assignee: LANXESS AG - US2005/80047, 2005, A1
Location in patent: Page/Page column 10
[3]Akiya; Osawa
[Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1954, vol. 74, p. 1259,1261][Chem.Abstr., 1955, p. 14649]

* For details of the synthesis route, please refer to the original source to ensure accuracy.