2,2'-Biquinoline

• CAS: 119-91-5
• Catalog Number: ACM119915-1
• Category: Quinolines
• Molecular Weight: 256.30
• Molecular Formula: C18H12N2
• Synonyms: Cuproin; 2,2'-Diquinolyl
• IUPAC Name: 2-quinolin-2-ylquinoline
• Canonical SMILES: C1=CC=C2C(=C1)C=CC(=N2)C3=NC4=CC=CC=C4C=C3
• InChI: WPTCSQBWLUUYDV-UHFFFAOYSA-N
• InChI Key: InChI=1S/C18H12N2/c1-3-7-15-13(5-1)9-11-17(19-15)18-12-10-14-6-2-4-8-16(14)20-18/h1-12H
• Melting Point: 192-195 °C-lit.
• Solubility: 3.98e-06 M
• Appearance: Powder or crystal
• Storage: Store at +15°C to +25°C.
• Complexity: 297
• Covalently-Bonded Unit Count: 1
• EC Number: 204-357-5
• Exact Mass: 256.100048391
• H-Bond Acceptor: 2
• Heavy Atom Count: 20
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 0
• Monoisotopic Mass: 256.100048391
• NSC Number: 1533
• Octanol Water Partition Coefficient: 4.31 (LogP)
• Rotatable Bond Count: 1
• Topological Polar Surface Area: 25.8 Ų
• UNII: 6RO6GA6RP3

Custom Q&A

What is the molecular formula of 2,2'-Biquinoline?

The molecular formula of 2,2'-Biquinoline is C18H12N2.

What is the melting point of 2,2'-Biquinoline?

The melting point of 2,2'-Biquinoline is 192-195 °C.

What is the color of 2,2'-Biquinoline?

2,2'-Biquinoline is slightly yellow to light beige in color.

What is the CAS number for 2,2'-Biquinoline?

The CAS number for 2,2'-Biquinoline is 119-91-5.

What is the water solubility of 2,2'-Biquinoline?

2,2'-Biquinoline is sparingly soluble in water (0.001g/L).

What is the application of 2,2'-Biquinoline?

2,2'-Biquinoline, also known as cuprous reagent, is highly selective for the determination of cuprous and can be used as a ligand in the synthesis of heteroleptic Cu(I) complexes for LEDs.

How is 2,2'-Biquinoline used in chemical analysis?

2,2'-Biquinoline is used as a reagent for the spectrophotometric determination of Cu and as an indicator for titration of organolithium reagents.

What is the boiling point of 2,2'-Biquinoline?

The boiling point of 2,2'-Biquinoline is estimated to be 389.54°C.

How is 2,2'-Biquinoline purified?

2,2'-Biquinoline is decolourized in CHCl3 solution using charcoal, then crystallized to a constant melting point from EtOH or pet ether.

What are the safety statements associated with 2,2'-Biquinoline?

The safety statements associated with 2,2'-Biquinoline are 26-36-37/39, indicating it should be kept away from sources of ignition and in a sealed container at room temperature.

Synthetic Use

Upstream Synthesis Route 1

• 91-22-5

• 4491-33-2
• 119-91-5

Reference: [1] Pharmazie, 1990, vol. 45, # 12, p. 900 - 904

Upstream Synthesis Route 2

• 91-22-5
• 75-00-3
• 124-38-9

• 4491-33-2
• 119-91-5

Reference: [1] Pharmazie, 1990, vol. 45, # 12, p. 900 - 904

Upstream Synthesis Route 3

• 21948-80-1
• 87512-28-5

• 119-91-5
• 53344-72-2

Reference: [1] Bulletin of the Chemical Society of Japan, 1989, vol. 62, # 12, p. 3848 - 3850

Upstream Synthesis Route 4

• 91-22-5

• 119-91-5

Reference: [1]Xie, Wen Wen; Liu, Yue; Yuan, Rui; Zhao, Dan; Yu, Tian Zhi; Zhang, Jian; Da, Chao Shan
[Advanced Synthesis and Catalysis, 2016, vol. 358, # 6, p. 994 - 1002]

Upstream Synthesis Route 5

• 2005-43-8

• 119-91-5

Reference: [1]Location in patent: experimental part
Aksenov; Goncharov
[Chemistry of Heterocyclic Compounds, 2008, vol. 44, # 12, p. 1491 - 1492]
[2]Dumouchel, Sylvain; Mongin, Florence; Trécourt, François; Quéguiner, Guy
[Tetrahedron, 2003, vol. 59, # 43, p. 8629 - 8640]
[3]Nakano
[Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1959, vol. 79, p. 310,313][Chem.Abstr., 1959, p. 16134]
[4]Dumouchel, Sylvain; Mongin, Florence; Trécourt, François; Quéguiner, Guy
[Tetrahedron Letters, 2003, vol. 44, # 19, p. 3877 - 3880]

Upstream Synthesis Route 6

• 1011-47-8
• 529-23-7

• 119-91-5

Reference: [1]Helvetica Chimica Acta,1921,vol. 4,p. 807